Western Blot (WB)
(Western Blot: Sample: Lane1: Porcine Liver Tissue; Lane2: Porcine Heart Tissue.)
Mouse Peroxisome Proliferator Activated Receptor Gamma Monoclonal Antibody | anti-PPARg antibody
Peroxisome Proliferator Activated Receptor Gamma (PPARg) Monoclonal Antibody
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Lane1: Porcine Liver Tissue; Lane2: Porcine Heart Tissue.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Porcine Liver Tissue; Lane2: Porcine Heart Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PPARg, Rat.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PPARg, Rat.)
NCBI and Uniprot Product Information
NCBI Description
ligand-activated transcription factor; mediates expression of genes involved in lipid metabolism [RGD, Feb 2006]
Uniprot Description
PPAR-gamma: a transcription factor, member of the nuclear hormone receptor superfamily. Receptor for hypolipidemic drugs and fatty acids. Preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Regulator of adipogenesis and lipid metabolism, modulates insulin sensitivity, cell proliferation and inflammation. Phosphorylated and inhibited by MAP kinase. Heterodimerizes with the retinoid X receptor. Interacts with NCOA6 coactivator, leading to a strong increase in transcription of target genes. Two splice-variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of Human Ortholog: 4q42
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleus; perinuclear region of cytoplasm; protein complex
Molecular Function: activating transcription factor binding; alpha-actinin binding; arachidonic acid binding; chromatin binding; DBD domain binding; DNA binding; DNA binding transcription factor activity; double-stranded DNA binding; drug binding; enzyme binding; estrogen receptor binding; identical protein binding; LBD domain binding; ligand-dependent nuclear receptor activity; ligand-dependent nuclear receptor transcription coactivator activity; peptide binding; protein binding; protein C-terminus binding; protein heterodimerization activity; protein phosphatase binding; protein self-association; retinoid X receptor binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor binding; zinc ion binding
Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process; brown fat cell differentiation; cell fate commitment; cell maturation; cellular response to insulin stimulus; diet induced thermogenesis; epithelial cell differentiation; fat cell differentiation; fatty acid metabolic process; fatty acid oxidation; glucose homeostasis; heart development; lipoprotein transport; long-chain fatty acid transport; low-density lipoprotein receptor biosynthetic process; monocyte differentiation; negative regulation of acute inflammatory response; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of collagen biosynthetic process; negative regulation of cytokine production; negative regulation of smooth muscle cell proliferation; negative regulation of telomerase activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; organ regeneration; placenta development; positive regulation of apoptosis; positive regulation of DNA binding; positive regulation of fat cell differentiation; positive regulation of fatty acid oxidation; positive regulation of oligodendrocyte differentiation; positive regulation of phagocytosis, engulfment; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of blood pressure; regulation of circadian rhythm; regulation of fat cell differentiation; regulation of gene expression; regulation of lipid metabolic process; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; response to caffeine; response to cold; response to dietary excess; response to drug; response to estrogen; response to food; response to light stimulus; response to lipid; response to low density lipoprotein stimulus; response to mechanical stimulus; response to organic cyclic compound; response to organic substance; response to retinoic acid; response to starvation; response to vitamin A; rhythmic process; signal transduction; steroid hormone mediated signaling; transcription, DNA-dependent; white fat cell differentiation
Research Articles on PPARg
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Product Notes
The PPARg pparg (Catalog #AAA2032027) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Peroxisome Proliferator Activated Receptor Gamma (PPARg) Monoclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Peroxisome Proliferator Activated Receptor Gamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western Blot: 1:100-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PPARg pparg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxisome Proliferator Activated Receptor Gamma, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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