Rabbit anti-Rat PEDF Monoclonal Antibody | anti-SerpinF1 antibody
Recombinant Anti-PEDF Antibody, Rabbit Monoclonal
Gene Names
Serpinf1; Pedf; Dmrs91
Reactivity
Rat
Applications
ELISA
Purity
Protein A
Synonyms
PEDF; Monoclonal Antibody; Recombinant Anti-PEDF Antibody; Rabbit Monoclonal; SerpinF1/PEDF Antibody; Rabbit MAb; serpin peptidase inhibitor; clade F; member 1; anti-SerpinF1 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
061
Specificity
Rat SerpinF1/PEDF
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SerpinF1 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Rat SerpinF1/PEDF Protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Rat SerpinF1/PEDF (rR SerpinF1/PEDF).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-SerpinF1 antibody
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression.
References
Ren, JG. et al., 2005, Med Hypotheses. 64 (1): 74-8. Filleur, S. et al., 2009. J Cell Biochem. 106 (5): 769-75. Kawaguchi, T. et al., 2010, Curr Mol Med. 10 (3): 302-11. Yamagishi, SI. et al., 2010, Curr Mol Med. 10 (3): 284-91. Nakamura, T. et al., 2010, Curr Mol Med. 10 (3): 312-6.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,465 Da
NCBI Official Full Name
pigment epithelium-derived factor
NCBI Official Synonym Full Names
serpin family F member 1
NCBI Official Symbol
Serpinf1
NCBI Official Synonym Symbols
Pedf; Dmrs91
NCBI Protein Information
pigment epithelium-derived factor
UniProt Protein Name
Alpha-2 antiplasmin
Protein Family
UniProt Gene Name
Serpinf1
NCBI Description
mouse homolog is a proteinase inhibitor involved in vascularization [RGD, Feb 2006]
Research Articles on SerpinF1
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Product Notes
The SerpinF1 serpinf1 (Catalog #AAA8113040) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-PEDF Antibody, Rabbit Monoclonal reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PEDF can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000. Researchers should empirically determine the suitability of the SerpinF1 serpinf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEDF, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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