Mouse anti-Human PDL1 Monoclonal Antibody | anti-PDL1 antibody
Anti PDL1 mouse monoclonal antibody
Reactivity
Human
Applications
Western Blot
Purity
Protein G purified from mice ascites
Synonyms
PDL1; Monoclonal Antibody; Anti PDL1 mouse monoclonal antibody; B7 homolog 1; B7-H; B7-H1; B7H1; PD-L1; CD274; anti-PDL1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10A11
Purity/Purification
Protein G purified from mice ascites
Form/Format
Liquid. Supplied as solution form in PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Applicable Applications for anti-PDL1 antibody
Western Blot (WB)
Application Notes
WB: 1:1,000-4,000
Immunogen
Plasmid of full length human PDL1
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at 4 degree C for frequent use. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Related Product Information for anti-PDL1 antibody
Programmed cell death ligand 1 (PD-L1, CD274, or B7-H1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested as a negative regulator of T and B cell, and plays important role in mediating tolerance of lymphocytes to self-antigens. It is also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD-1-independent manner. PD-L1 is a 290 aa transmembrane protein with a calculated molecular weight of 33 kDa, it is predicted to be 27-30 kDa after signal peptide cleavage (PMID: 25609200; 17076679). The apparent molecular weight has also been reported as 45-70 kDa, major glycosylated form of 45-50 kDa and multiple post-translational modifications form of 65-70 kDa (PMID: 18760278; 16493058).
Product Categories/Family for anti-PDL1 antibody
NCBI and Uniprot Product Information
UniProt Accession #
Similar Products
Product Notes
The PDL1 (Catalog #AAA157749) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti PDL1 mouse monoclonal antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1,000-4,000. Researchers should empirically determine the suitability of the PDL1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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