Mouse PCGF2 Monoclonal Antibody | anti-PCGF2 antibody

PCGF2 (polycomb Group Ring Finger 2, MEL-18, MGC10545, RNF110, ZNF144) (Biotin)

Cat. Num. AAA6172792

• Gene Names: PCGF2; TPFS; MEL-18; RNF110; ZNF144
• Applications: Western Blot
• Purity: Purified
• Synonyms: PCGF2; Monoclonal Antibody; PCGF2 (polycomb Group Ring Finger 2; MEL-18; MGC10545; RNF110; ZNF144) (Biotin); polycomb Group Ring Finger 2; ZNF144; anti-PCGF2 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 2D6
• Specificity: Recognizes PCGF2.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 344

• Applicable Applications for anti-PCGF2 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: PCGF2 (AAH04858.1, 236aa-294aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: LTLATVPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPPA
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PCGF2 monoclonal antibody (M05), clone 2D6. Western Blot analysis of PCGF2 expression in human placenta.)

Related Product Information for anti-PCGF2 antibody

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq]

Product Categories/Family for anti-PCGF2 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 13436062
• NCBI GeneID: 7703
• NCBI Official Full Name: Polycomb group ring finger 2
• NCBI Official Synonym Full Names: polycomb group ring finger 2
• NCBI Official Symbol: PCGF2
• NCBI Official Synonym Symbols: TPFS; MEL-18; RNF110; ZNF144
• NCBI Protein Information: polycomb group RING finger protein 2
• Protein Family: Polycomb group RING finger protein

NCBI Description

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]