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Western Blot (WB) (Western Blot; Sample: Recombinant PTHR2, Human.)

Mouse anti-Human Parathyroid Hormone Receptor 2 (PTHR2) Monoclonal Antibody | anti-PTHR2 antibody

Monoclonal Antibody to Parathyroid Hormone Receptor 2 (PTHR2)

Gene Names
PTH2R; PTHR2
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G Affinity Chromatography
Synonyms
Parathyroid Hormone Receptor 2 (PTHR2); Monoclonal Antibody; Monoclonal Antibody to Parathyroid Hormone Receptor 2 (PTHR2); PTH2; PTH2R; Parathyroid Hormone 2 Receptor; anti-PTHR2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
C1
Specificity
The antibody is a mouse monoclonal antibody raised against PTHR2. It has been selected for its ability to recognize PTHR2 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G Affinity Chromatography
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence
Asp27~Tyr145
Applicable Applications for anti-PTHR2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.5-5ug/mL
IHC: 5-30ug/mL
ICC: 5-30ug/mL
Immunogen Sequence
Asp27~Tyr145
Cross Reactivity
Human
Conjugation
None
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot; Sample: Recombinant PTHR2, Human.)

Western Blot (WB) (Western Blot; Sample: Recombinant PTHR2, Human.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 40ug/ml Mouse Anti-Human PTHR2 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 40ug/ml Mouse Anti-Human PTHR2 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Cerebellum Tissue; Primary Ab: 40ug/ml Mouse Anti-Human PTHR2 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Cerebellum Tissue; Primary Ab: 40ug/ml Mouse Anti-Human PTHR2 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 40ug/ml Mouse Anti-Human PTHR2 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 40ug/ml Mouse Anti-Human PTHR2 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Product Categories/Family for anti-PTHR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
550
NCBI Official Full Name
Parathyroid hormone 2 receptor
NCBI Official Synonym Full Names
parathyroid hormone 2 receptor
NCBI Official Symbol
PTH2R
NCBI Official Synonym Symbols
PTHR2
NCBI Protein Information
parathyroid hormone 2 receptor; PTH2 receptor; parathyroid hormone receptor 2
UniProt Protein Name
Parathyroid hormone 2 receptor
UniProt Gene Name
PTH2R
UniProt Synonym Gene Names
PTHR2; PTH2 receptor
UniProt Entry Name
PTH2R_HUMAN

NCBI Description

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Uniprot Description

PTH2R: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 2; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: parathyroid hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on PTHR2

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Product Notes

The PTHR2 pth2r (Catalog #AAA2111549) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Parathyroid Hormone Receptor 2 (PTHR2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Parathyroid Hormone Receptor 2 (PTHR2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.5-5ug/mL IHC: 5-30ug/mL ICC: 5-30ug/mL. Researchers should empirically determine the suitability of the PTHR2 pth2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Asp27~Tyr1 45. It is sometimes possible for the material contained within the vial of "Parathyroid Hormone Receptor 2 (PTHR2), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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