Related Product Information for anti-ODC1 antibody
Ornithine decarboxylase (ODC), the first enzyme in polyamine synthesis, is a transcriptional target of YC and a modifier of APC -dependent tumorigenesis. It is located to 2p25. There is considerable genetic homology between a region of mouse chromosome 12 and the distal short arm of human chromosome 2. Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA.
Product Categories/Family for anti-ODC1 antibody
NCBI Description
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq]
Uniprot Description
ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]
Protein type: Cell cycle regulation; Lyase; EC 4.1.1.17; Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - glutathione
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; cytosol
Molecular Function: protein homodimerization activity; ornithine decarboxylase activity
Biological Process: response to virus; positive regulation of cell proliferation; regulation of protein catabolic process; regulation of amino acid metabolic process; kidney development; putrescine biosynthetic process from ornithine; polyamine metabolic process
Disease: Colorectal Cancer
Product Notes
The ODC1 odc1 (Catalog #
AAA633574) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Ornithine Decarboxylase (ODC, Dodc1, Ornithine Decarboxylase 1, Odc1, Ornithine Decarboxylase 2, ODC2, ODCP, Ornithine Decarboxylase Structural 1, RNODC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Ornithine Decarboxylase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunoprecipitation, and Immunohistochemistry. Dilution: Western Blot: 4ug/ml Immunohistochemistry (paraffin): 8g/ml. Researchers should empirically determine the suitability of the ODC1 odc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"Ornithine Decarboxylase, Monoclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
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industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
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