Testing Data
(Human HeLa cells were stained with monoclonal antibody MBS6005035, which binds to a nuclear pore complex antigen, and chicken antibody to vimentin 031441. Note the close apposition of cytoplasmic vimentin intermediate filaments with the nuclear membrane, revealed by the MBS6005035 binding to the nuclear pores.)
Mouse Nuclear Pore Complex, Panspecific Monoclonal Antibody | anti-NUP133 antibody
Nuclear Pore Complex, Panspecific
Sterile-filtered cell culture fluid from an Integra CL-350 biochamber
Sterile-filtered cell culture fluid from an Integra CL-350 biochamber
Dilution: Immunofluorescence: For yeast cells, try diluted 1:100-1:500. For immunofluorescence on mammalian cells try at 1:50-1:100.
Testing Data
(Human HeLa cells were stained with monoclonal antibody MBS6005035, which binds to a nuclear pore complex antigen, and chicken antibody to vimentin 031441. Note the close apposition of cytoplasmic vimentin intermediate filaments with the nuclear membrane, revealed by the MBS6005035 binding to the nuclear pores.)
Testing Data
(Human HeLa cells were stained with monoclonal antibody MBS6005035, which binds to a nuclear pore complex antigen, and chicken antibody to vimentin 031441. Note the close apposition of cytoplasmic vimentin intermediate filaments with the nuclear membrane, revealed by the MBS6005035 binding to the nuclear pores.)
NCBI and Uniprot Product Information
NCBI Description
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. [provided by RefSeq, Jul 2008]
Uniprot Description
NUP133: Involved in poly(A)+ RNA transport. Belongs to the nucleoporin Nup133 family.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 1q42.13
Cellular Component: nuclear membrane; membrane; nuclear envelope; nuclear pore; outer kinetochore of condensed chromosome; cytosol
Molecular Function: protein binding; nucleocytoplasmic transporter activity
Biological Process: paraxial mesoderm development; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; nuclear pore organization and biogenesis; mRNA export from nucleus; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport
Research Articles on NUP133
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Product Notes
The NUP133 nup133 (Catalog #AAA6005035) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Nuclear Pore Complex, Panspecific reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nuclear Pore Complex, Panspecific can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). Suitable for use in Immunofluorescence. Dilution: Immunofluorescence: For yeast cells, try diluted 1:100-1:500. For immunofluorescence on mammalian cells try at 1:50-1:100. Researchers should empirically determine the suitability of the NUP133 nup133 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nuclear Pore Complex, Panspecific, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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