Mouse anti-Human NTF2 Monoclonal Antibody | anti-NTF2 antibody

NTF2 Mouse Monoclonal

Cat. Num. AAA7602114

• Gene Names: NUTF2; NTF2; PP15; NTF-2
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunofluorescence, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Protein A+G purification
• Synonyms: NTF2; Monoclonal Antibody; NTF2 Mouse Monoclonal; anti-NTF2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a
• Purity/Purification: >=95% as determined by SDS-PAGE; Protein A+G purification
• Form/Format: Liquid
• Sequence Length: 127

• Applicable Applications for anti-NTF2 antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
• Immunogen: Nuclear transport factor 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissue slide using MBS7602114 (NUTF2 antibody) at dilution of 1:100)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS7602114 (NUTF2 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 5031985
• NCBI GeneID: 10204
• NCBI Accession #: NP_005787.1
• NCBI GenBank Nucleotide #: NM_005796.2
• Molecular Weight: 14,478 Da
• NCBI Official Full Name: nuclear transport factor 2
• NCBI Official Synonym Full Names: nuclear transport factor 2
• NCBI Official Symbol: NUTF2
• NCBI Official Synonym Symbols: NTF2; PP15; NTF-2
• NCBI Protein Information: nuclear transport factor 2
• UniProt Protein Name: Nuclear transport factor 2
• Protein Family: Nuclear transport factor
• UniProt Gene Name: NUTF2
• UniProt Synonym Gene Names: NTF2; NTF-2; PP15
• UniProt Entry Name: NTF2_HUMAN

NCBI Description

This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]

Uniprot Description

NUTF2: Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import. Homodimer.

Protein type: Nuclear import

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytosol; nuclear outer membrane; nuclear pore

Molecular Function: protein binding; Ran GTPase binding; transporter activity

Biological Process: positive regulation of protein import into nucleus; protein export from nucleus; protein import into nucleus, translocation