Mouse anti-Rabbit NP-5 Monoclonal Antibody | anti-LOC100009136 antibody
NP-5 (Neutrophil Defensin 5, Microbicidal Peptide NP-5, Neutrophil Antibiotic Peptide NP-5)
Gene Names
LOC100009136; CS-6; NP-5
Reactivity
Rabbit
Applications
ELISA, Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
NP-5; Monoclonal Antibody; NP-5 (Neutrophil Defensin 5; Microbicidal Peptide NP-5; Neutrophil Antibiotic Peptide NP-5); Anti -NP-5 (Neutrophil Defensin 5; anti-LOC100009136 antibody
Host
Mouse
Reactivity
Rabbit
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
R3
Specificity
Recognizes natural, synthetic and recombinant rabbit NP-5.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Applicable Applications for anti-LOC100009136 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunohistochemistry.
Dilution: Flow Cytometry: 1:10
Western Blot: 1:10
Immunohistochemistry (Frozen, paraffin): 1:10
Dilution: Flow Cytometry: 1:10
Western Blot: 1:10
Immunohistochemistry (Frozen, paraffin): 1:10
Immunogen
NP-5
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-LOC100009136 antibody
Alpha defensins belong together with the beta defensins to the family of cationic trisulfide containing microbicidal peptides. They exert their microbicidal activity by permeating the membrane involving the formation of voltage regulated ion channels. Rabbit neutrophils contain large amount of alpha defensins (Neutrophil Defensin) NP 1-6. Defensins constitute more than 15% of total protein in rabbit neutrophils and are accumulated in dense cytoplasmic granules. Rabbit neutrophils express all six rabbit alpha defensins, NP 1-6. Among myeloid rabbit alpha defensins NP1-6, NP 3 -6 are neutrophil specific, while NP 1-2 are expressed in rabbit alveolar macrophages. Defensins are relatively resistant to proteolysis, low pH and boiling. Rabbit neutrophil defensins, whose three dimensiol structures are very similar to those of human alpha defensins may be helpful in understanding the role of antimicrobial peptides in innate and acquired immunity and in the studies on the role of neutrophils in pathological situations and in various rabbit models of human diseases
Product Categories/Family for anti-LOC100009136 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,122 Da
NCBI Official Full Name
neutrophil antibiotic peptide NP-5
NCBI Official Symbol
LOC100009136
NCBI Official Synonym Symbols
CS-6; NP-5
NCBI Protein Information
neutrophil antibiotic peptide NP-5; defensin np-5; corticostatin CS-6; microbicidal peptide NP-5
UniProt Protein Name
Neutrophil antibiotic peptide NP-5
UniProt Entry Name
DEF6_RABIT
Uniprot Description
Function: Microbicidal activity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the alpha-defensin family.
Similar Products
Product Notes
The LOC100009136 (Catalog #AAA633198) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NP-5 (Neutrophil Defensin 5, Microbicidal Peptide NP-5, Neutrophil Antibiotic Peptide NP-5) reacts with Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's NP-5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunohistochemistry. Dilution: Flow Cytometry: 1:10 Western Blot: 1:10 Immunohistochemistry (Frozen, paraffin): 1:10. Researchers should empirically determine the suitability of the LOC100009136 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NP-5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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