Western Blot (WB)
(Immunoblots using NMDAR1 antibody (1:1000) to detect oocytes expressing either wt or NMDAR1 mutant receptors. M1 indicates the expected band position of the NMDAR1 monomer (~110 kDa) and D1, the NMDAR1 homodimer (~220 kDa). * indicates non-specific bands seen with the NMDAR1 antibody.)
Mouse NMDAR1 Monoclonal Antibody | anti-NMDAR1 antibody
NMDAR1 antibody
Gene Names
GRIN1; NMDAR1
Applications
ELISA, Immunohistochemistry, Immunohistochemistry, Immunocytochemistry, immunoassay, Radioimmunoassay
Purity
NMDAR1 antibody was purified by Protein A chromatography
Synonyms
NMDAR1; Monoclonal Antibody; NMDAR1 antibody; Monoclonal NMDAR1; Anti-NMDAR1; NMDAR 1; NMDAR-1; Glutamate receptor ionotropic N-methyl D-aspartate 1; GluN1; NMDR1; NMD-R1; NMD R1; GRIN1; NR1 antihody; NMDA 1; NMDA-1; anti-NMDAR1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
54.1
Specificity
Recognizes an epitope between amino acids 660-811 of the NMDAR1 receptor
Purity/Purification
NMDAR1 antibody was purified by Protein A chromatography
Form/Format
Supplied in PBS buffer with no preservative
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
138
Applicable Applications for anti-NMDAR1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Immunocytochemistrey (ICC), Radioimmunoassay (RIA)
Application Notes
IHC: 1:500-2000
Biological Significance
NMDAR1 a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission.
Cross-Reactivity
Human, Rat, Monkey, Xenopus. No cross-reactivity with NMDAR2, NMDAR3, NMDAR4 or NMDAR5
Immunogen
NMDAR1 antibody was raised in Mouse using recombinant fusion protein containing GST and NMDAR1 aa. 660-811 as the immunogen
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Stable for 1 year at -20 degree C from date of receipt
Western Blot (WB)
(Immunoblots using NMDAR1 antibody (1:1000) to detect oocytes expressing either wt or NMDAR1 mutant receptors. M1 indicates the expected band position of the NMDAR1 monomer (~110 kDa) and D1, the NMDAR1 homodimer (~220 kDa). * indicates non-specific bands seen with the NMDAR1 antibody.)
Western Blot (WB)
(Immunoblots using NMDAR1 antibody (1:1000) to detect oocytes expressing either wt or NMDAR1 mutant receptors. M1 indicates the expected band position of the NMDAR1 monomer (~110 kDa) and D1, the NMDAR1 homodimer (~220 kDa). * indicates non-specific bands seen with the NMDAR1 antibody.)
Immunofluorescence (IF)
(Fluorescence immunocytochemical images of the cultured hippocampal neurons. Green (A, B, C) fluorescence represents NMDAR 1A in neurons cultured with 0, 37 and 74 uM Aluminium Lactate for 7 days (PND 10). White arrows label the cell disruption and white line shows the scale bar expressed as 50 um.)
Immunofluorescence (IF)
(Fluorescence immunocytochemical images of the cultured hippocampal neurons. Green (A, B, C) fluorescence represents NMDAR 1A in neurons cultured with 0, 37 and 74 uM Aluminium Lactate for 7 days (PND 10). White arrows label the cell disruption and white line shows the scale bar expressed as 50 um.)
Related Product Information for anti-NMDAR1 antibody
Mouse monoclonal NMDAR1 antibody
Product Categories/Family for anti-NMDAR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
15,584 Da
NCBI Official Full Name
NMDAR1, partial
NCBI Official Symbol
GRIN1
NCBI Official Synonym Symbols
NMDAR1
NCBI Protein Information
glutamate receptor ionotropic, NMDA 1
UniProt Protein Name
NMDAR1
Protein Family
UniProt Gene Name
NMDAR1
UniProt Entry Name
Q76MQ9_TAEGU
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Product Notes
The NMDAR1 nmdar1 (Catalog #AAA838158) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NMDAR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Immunocytochemistrey (ICC), Radioimmunoassay (RIA). IHC: 1:500-2000. Researchers should empirically determine the suitability of the NMDAR1 nmdar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NMDAR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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