Western Blot (WB)
(Western Blot:Sample: Recombinant MSTN, Human.)
Mouse Myostatin Monoclonal Antibody | anti-MSTN antibody
Myostatin (MSTN) Monoclonal Antibody
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot:Sample: Recombinant MSTN, Human.)
Western Blot (WB)
(Western Blot:Sample: Recombinant MSTN, Human.)
Western Blot (WB)
(Western Blot;Sample: Rat Heart lysate;Primary Ab: 2ug/ml Mouse Anti-Human MSTN AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))
Western Blot (WB)
(Western Blot;Sample: Rat Heart lysate;Primary Ab: 2ug/ml Mouse Anti-Human MSTN AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Liver Tissue;Primary Ab: 20ug/ml Mouse Anti-Human MSTN AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Liver Tissue;Primary Ab: 20ug/ml Mouse Anti-Human MSTN AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Uniprot Description
MSTN: Acts specifically as a negative regulator of skeletal muscle growth. Defects in MSTN are the cause of muscle hypertrophy (MSLHP). MSLHP is a condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong. Belongs to the TGF-beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2q32.2
Cellular Component: cytoplasm; extracellular space
Molecular Function: cytokine activity; growth factor activity; heparin binding; identical protein binding; protein binding; protein homodimerization activity; receptor binding; transforming growth factor beta receptor binding
Biological Process: cell development; muscle maintenance; muscle organ development; negative regulation of insulin receptor signaling pathway; negative regulation of kinase activity; negative regulation of muscle hypertrophy; negative regulation of myoblast differentiation; negative regulation of protein kinase B signaling cascade; negative regulation of skeletal muscle tissue growth; ovulation cycle process; positive regulation of transcription, DNA-templated; regulation of apoptosis; regulation of MAPK cascade; response to electrical stimulus; response to estrogen; response to ethanol; response to gravity; response to heat; response to muscle activity; response to testosterone stimulus; skeletal muscle atrophy; skeletal muscle tissue regeneration; transforming growth factor beta receptor signaling pathway
Disease: Muscle Hypertrophy
Research Articles on MSTN
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Product Notes
The MSTN mstn (Catalog #AAA2032052) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Myostatin (MSTN) Monoclonal Antibody reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Myostatin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the MSTN mstn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Myostatin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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