Mouse anti-Human MPP3 Monoclonal Antibody | anti-MPP3 antibody

MPP3 (MAGUK p55 Subfamily Member 3, Discs Large Homolog 3, DLG3, Protein MPP3) (PE)

Cat. Num. AAA6158879

• Gene Names: MPP3; DLG3
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MPP3; Monoclonal Antibody; MPP3 (MAGUK p55 Subfamily Member 3; Discs Large Homolog 3; DLG3; Protein MPP3) (PE); anti-MPP3 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 4D7
• Specificity: Recognizes human MPP3.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 2129

• Applicable Applications for anti-MPP3 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-585 from human MPP3 (AAH56865) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MPVLSEDSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR
• Conjugate: PE
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (90.09kD).)

Western Blot (WB)

(Western Blot analysis of MPP3 expression in transfected 293T cell line by MPP3 monoclonal antibody. Lane 1: MPP3 transfected lysate (66.2kD). Lane 2: Non-transfected lysate.)

Testing Data

(Detection limit for recombinant GST tagged MPP3 is ~0.03ng/ml as a capture antibody.)

Western Blot (WB)

(Western blot analysis of MPP3 over-expressed 293 cell line, cotransfected with MPP3 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MPP3 monoclonal antibody GAPDH (36.1kD) used as specificity and loading control.)

Related Product Information for anti-MPP3 antibody

This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq]

Product Categories/Family for anti-MPP3 antibody

Antibodies; Membrane Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 34785138
• NCBI GeneID: 4356
• NCBI Official Full Name: Homo sapiens membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3), mRNA
• NCBI Official Synonym Full Names: membrane palmitoylated protein 3
• NCBI Official Symbol: MPP3
• NCBI Official Synonym Symbols: DLG3
• NCBI Protein Information: MAGUK p55 subfamily member 3
• Protein Family: MAGUK p55 subfamily

NCBI Description

This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]