Immunohistochemistry (IHC)
(Anti-MESDC2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Rabbit MESDC2/MESD Monoclonal Antibody | anti-MESDC2/MESD antibody
Anti-MESDC2/MESD Antibody
Gene Names
MESD; BOCA; MESDC2
Reactivity
HumanPredicted: Mouse, Rat, Monkey
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Tissue culture supernatant
Synonyms
MESDC2/MESD; Monoclonal Antibody; Anti-MESDC2/MESD Antibody; Rabbit Monoclonal (IgG) to Human MESDC2/MESD; MESDC2; BOCA; Mesoderm development protein; MESD; KIAA0081; LDLR chaperone MESD; anti-MESDC2/MESD antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat, Monkey
Predicted: Mouse, Rat, Monkey
Clonality
Monoclonal
Isotype
IgG
Specificity
MESDC2 (C22F5) Rabbit mAb detects endogenous levels of total MESDC2 protein.
Purity/Purification
Tissue culture supernatant
Form/Format
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100 ug/ml BSA, 50% glycerol, 0.02% sodium azide.
Sequence Length
234
Applicable Applications for anti-MESDC2/MESD antibody
Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB)
Application Notes
IHC-P: 1:100
IP: 1:50
WB: 1:1000
IP: 1:50
WB: 1:1000
Immunogen
Immunizing rabbits with a recombinant human MESDC2 protein.
Conjugation
Unconjugated
Preparation and Storage
May be stored at 4 degree C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20 degree C.
Aliquots are stable for at least 12 months.
Aliquot to avoid repeated freezing and thawing.
Store at -20 degree C.
Aliquots are stable for at least 12 months.
Immunohistochemistry (IHC)
(Anti-MESDC2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Immunohistochemistry (IHC)
(Anti-MESDC2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Immunohistochemistry (WB)
(Anti-MESDC2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Immunohistochemistry (WB)
(Anti-MESDC2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Related Product Information for anti-MESDC2/MESD antibody
Chaperone specifically assisting the folding of beta-propeller/EGFmodules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasmamembrane. Essential for specification of embryonic polarity and mesoderminduction.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,895 Da
NCBI Official Full Name
LRP chaperone MESD
NCBI Official Synonym Full Names
mesoderm development LRP chaperone
NCBI Official Symbol
MESD
NCBI Official Synonym Symbols
BOCA; MESDC2
NCBI Protein Information
LRP chaperone MESD
UniProt Protein Name
LRP chaperone MESD
UniProt Gene Name
MESD
Uniprot Description
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells ().
Research Articles on MESDC2/MESD
Similar Products
Product Notes
The MESDC2/MESD mesd (Catalog #AAA2400591) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MESDC2/MESD Antibody reacts with Human Predicted: Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's MESDC2/MESD can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB). IHC-P: 1:100 IP: 1:50 WB: 1:1000. Researchers should empirically determine the suitability of the MESDC2/MESD mesd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MESDC2/MESD, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
