Rat anti-Human Membrane Frizzled-Related Protein Monoclonal Antibody | anti-MFRP antibody
Membrane Frizzled-Related Protein (Membrane-type Frizzled-Related Protein, MFRP)
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: Western Blot: 1-2ug/ml
Immunohistochemistry: 5-15ug/ml
ELISA: 0.5-1ug/ml
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.
Uniprot Description
MFRP: May play a role in eye development. Defects in MFRP are the cause of nanophthalmos 2 (NNO2). NNO2 is a rare autosomal recessive disorder of eye development characterized by extreme hyperopia and small functional eyes. Defects in MFRP are the cause of microphthalmia isolated type 5 (MCOP5). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataract and other abnormalities like cataract may also be present. MCOP5 is characterized by posterior microphthalmia, retinitis pigmentosa, foveoschisis and optic disc drusen.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q23
Cellular Component: apical plasma membrane; integral to membrane
Biological Process: embryonic development
Disease: Microphthalmia, Isolated 5; Nanophthalmos 2
Research Articles on MFRP
Similar Products
Product Notes
The MFRP mfrp (Catalog #AAA600569) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Membrane Frizzled-Related Protein (Membrane-type Frizzled-Related Protein, MFRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Membrane Frizzled-Related Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry and ELISA. Dilution: Western Blot: 1-2ug/ml Immunohistochemistry: 5-15ug/ml ELISA: 0.5-1ug/ml. Researchers should empirically determine the suitability of the MFRP mfrp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Membrane Frizzled-Related Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
