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Mouse anti-Human MDR1 Monoclonal Antibody | anti-MDR1 antibody

MDR1 (Multi Drug Resistance Protein 1, ABC20, ATP Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1) (Biotin)

Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Purified by Protein G Affinity Chromatography
Synonyms
MDR1; Monoclonal Antibody; MDR1 (Multi Drug Resistance Protein 1; ABC20; ATP Binding Cassette Subfamily B (MDR/TAP) Member 1; ABCB1; CD243; CLCS; GP170; P-Glycoprotein; P-gp; P Glycoprotein 1; PGY1) (Biotin); anti-MDR1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
9A183
Specificity
Recognizes an extracellular conformational epitope of CD243, also known as MDR1 (multi-drug resistance protein 1) and Pgp (P-glycoprotein). Species Crossreactivity: primate. Does not cross-react with mitochondrial pyruvate carboxylase, mouse, rat.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Applicable Applications for anti-MDR1 antibody
Flow Cytometry (FC/FACS)
Immunogen
Mouse Balb/c 3T3 fibroblasts transfected with human CD243 cDNA.
Conjugate
Biotin
Preparation and Storage
Store at -20 degree C.
Product Categories/Family for anti-MDR1 antibody
References
1. Mechetner, E.B and Roninson, I.B. (1992) Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. P.N.A.S. 89: 5824-5828. 2. Park, S.W. et al. (2003) Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. Cytometry Part A. 53A: 67-78. 3. Koziolek, M.J. et al. (2001) Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. Kid. Int. 60: 156-166. 4. Beck, W.T. et al. (1996) Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumours: Consensus recommendations. Cancer. Res. 56: 3010-3020.

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Product Notes

The MDR1 (Catalog #AAA6249137) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MDR1 (Multi Drug Resistance Protein 1, ABC20, ATP Binding Cassette Subfamily B (MDR/TAP) Member 1, ABCB1, CD243, CLCS, GP170, P-Glycoprotein, P-gp, P Glycoprotein 1, PGY1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MDR1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the MDR1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MDR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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