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Mouse MCP-3 Monoclonal Antibody | anti-MCP-3 antibody

mAb anti-human MCP-3

Reactivity
Human. Other species not tested
Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, SAA and EGF.
Applications
Western Blot
Purity
Protein G affinity purified
Synonyms
MCP-3; Monoclonal Antibody; mAb anti-human MCP-3; Macrophage/Monocyte Chemotactic Protein (MCP-3) ; Mouse monoclonal antibody to human macrophage/monocyte chemotactic protein-3 (MCP-3); anti-MCP-3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human. Other species not tested
Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, SAA and EGF.
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
768
Specificity
Reactive with natural and recombinant human Macrophage/Monocyte Chemotactic Protein (MCP-3)
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS, pH 7.2.
Sequence Length
109
Applicable Applications for anti-MCP-3 antibody
Western Blot (WB)
Application Notes
Western Blot: This antibody, when used at concentration of 0.5-2mug/mL will allow visualization of 0.1mug/lane of human MCP-3.
Target Protein
Human MCP-3
Immunogen
Recombinant human MCP-3 (M.W. 8.5kDa containing 76 amino acids residues)
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distillated water is recommended to reconstitute the antibody.
Research Area
Cytokine, chemotaxis.
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-MCP-3 antibody
Mouse monoclonal antibody to human macrophage/monocyte chemotactic protein-3 (MCP-3), Protein G affinity purified
Product Categories/Family for anti-MCP-3 antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
11,200 Da
NCBI Official Full Name
monocyte chemotactic protein-3
UniProt Protein Name
C-C motif chemokine 7
UniProt Gene Name
CCL7
UniProt Entry Name
CCL7_HUMAN

Uniprot Description

CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR1 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity

Biological Process: cellular calcium ion homeostasis; regulation of cell shape; monocyte chemotaxis; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; immune response; cytoskeleton organization and biogenesis; chemotaxis; signal transduction; inflammatory response; positive regulation of cell migration

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Product Notes

The MCP-3 ccl7 (Catalog #AAA592006) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-human MCP-3 reacts with Human. Other species not tested Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, SAA and EGF. and may cross-react with other species as described in the data sheet. AAA Biotech's MCP-3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: This antibody, when used at concentration of 0.5-2mug/mL will allow visualization of 0.1mug/lane of human MCP-3. Researchers should empirically determine the suitability of the MCP-3 ccl7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCP-3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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