Western Blot (WB)
(MC1R Antibody (Center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MC1R antibody detected the MC1R protein (arrow).)
Mouse anti-Human MC1R Monoclonal Antibody
MC1R, ID (MC1R, MSHR, Melanocyte-stimulating hormone receptor, Melanocortin receptor 1)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
PurifiedPurified by ammonium sulfate precipitation.
Synonyms
MC1R; Monoclonal Antibody; ID (MC1R; MSHR; Melanocyte-stimulating hormone receptor; Melanocortin receptor 1); Anti -MC1R; anti-MC1R antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgM
Clone Number
578CT6.2.3
Specificity
Human
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Applicable Applications for anti-MC1R antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA.
Dilution: ELISA: 1:1,000
Western Blot: 1:100~250
Dilution: ELISA: 1:1,000
Western Blot: 1:100~250
Immunogen
MC1R Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human MC1R.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(MC1R Antibody (Center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MC1R antibody detected the MC1R protein (arrow).)
Western Blot (WB)
(MC1R Antibody (Center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MC1R antibody detected the MC1R protein (arrow).)
Related Product Information for anti-MC1R antibody
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq].
Product Categories/Family for anti-MC1R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
MC1R, partial
Protein Family
Uniprot Description
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Similar Products
Product Notes
The MC1R (Catalog #AAA6006406) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MC1R, ID (MC1R, MSHR, Melanocyte-stimulating hormone receptor, Melanocortin receptor 1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MC1R can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA. Dilution: ELISA: 1:1,000 Western Blot: 1:100~250. Researchers should empirically determine the suitability of the MC1R for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MC1R, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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