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Western Blot (WB) (Western blot analysis of Matrin 3 on different lysates using anti-Matrin 3 antibody at 1/1, 000 dilution. Positive control: Lane 1: Daudi Lane 2: Mouse brain tissue)

Rabbit Matrin 3 Monoclonal Antibody | anti-MATR3 antibody

Matrin 3 Antibody

Gene Names
MATR3; MPD2; ALS21; VCPDM
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
ProA affinity purified
Synonyms
Matrin 3; Monoclonal Antibody; Matrin 3 Antibody; ALS21 antibody; KIAA0723 antibody; Matr3 antibody; MATR3_HUMAN antibody; Matrin-3 antibody; Matrin3 antibody; MPD2 antibody; VCPDM antibody; Vocal cord and pharyngeal weakness with distal myopathy antibody; anti-MATR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
JU93-43
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-MATR3 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF),Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:1000-1:2000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC/FACS: 1:50-1:100
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of Matrin 3 on different lysates using anti-Matrin 3 antibody at 1/1, 000 dilution. Positive control: Lane 1: Daudi Lane 2: Mouse brain tissue)

Western Blot (WB) (Western blot analysis of Matrin 3 on different lysates using anti-Matrin 3 antibody at 1/1, 000 dilution. Positive control: Lane 1: Daudi Lane 2: Mouse brain tissue)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.)

Immunocytochemistry (ICC)

(ICC staining Matrin 3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Immunocytochemistry (ICC) (ICC staining Matrin 3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Immunocytochemistry (ICC)

(ICC staining Matrin 3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Immunocytochemistry (ICC) (ICC staining Matrin 3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Immunocytochemistry (ICC)

(ICC staining Matrin 3 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Immunocytochemistry (ICC) (ICC staining Matrin 3 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of LOVO cells with Matrin 3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of LOVO cells with Matrin 3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)
Related Product Information for anti-MATR3 antibody
Matrin-3 is a nuclear matrix protein containing one matrin-type zinc finger and two RRM (RNA recognition motif) domains. Matrin-3 plays a role in transcription and may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the PSF-p54/NRB heteromer, Matrin-3 may play a role in the nuclear retention of defective RNAs. As the main substrate for PKA-mediated phosphorylation, Matrin-3 may serve as a rapid way of transferring information from synapses containing NMDA receptors to neuronal nuclei under physiological conditions. Also, the phosphorylation of Matrin-3 may contribute to neuronal death under pathological conditions. It is likely that Matrin-3 activity is regulated by calcium dependent interaction with CaM I and also by caspase induced cleavage.
Product Categories/Family for anti-MATR3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,576 Da
NCBI Official Full Name
matrin-3 isoform a
NCBI Official Synonym Full Names
matrin 3
NCBI Official Symbol
MATR3
NCBI Official Synonym Symbols
MPD2; ALS21; VCPDM
NCBI Protein Information
matrin-3; vocal cord and pharyngeal weakness with distal myopathy
UniProt Protein Name
Matrin-3
Protein Family
UniProt Gene Name
MATR3
UniProt Synonym Gene Names
KIAA0723
UniProt Entry Name
MATR3_HUMAN

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Product Notes

The MATR3 matr3 (Catalog #AAA9436519) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Matrin 3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Matrin 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF),Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC: 1:50-1:200 FC/FACS: 1:50-1:100. Researchers should empirically determine the suitability of the MATR3 matr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Matrin 3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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