Mouse anti-Human MATN1 Monoclonal Antibody | anti-MATN1 antibody

MATN1 Antibody

Cat. Num. AAA9602524

• Gene Names: MATN1; CMP; CRTM
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence, Immunocytochemistry, ELISA
• Purity: Affinity-Chromatography
• Synonyms: MATN1; Monoclonal Antibody; MATN1 Antibody; Cartilage matrix protein; CMP; CRTM; Matn1; MATN1_HUMAN; Matrilin 1; Matrilin 1 cartilage matrix protein; Matrilin-1; anti-MATN1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Specificity: MATN1 antibody detects endogenous levels of total MATN1
• Purity/Purification: Affinity-Chromatography
• Form/Format: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 496

• Applicable Applications for anti-MATN1 antibody: Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
• Application Notes: ELISA: 1:10000; WB: 1:500-1:2000; ICC: 1:200-1:1000
• Immunogen: Purified recombinant fragment of human MATN1 expressed in E. Coli
• Subcellular Location: Secreted, Extracellular Space, Extracellular Matrix.
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Figure 1: Western blot analysis using MATN1 mAb against HEK293 (1) and MATN1(AA: 427-496)-hIgGFc transfected HEK293 (2) cell lysate.)

Related Product Information for anti-MATN1 antibody

Description: This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
Function: Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.
Subunit Structure: Homotrimer. Interacts with COMP.

NCBI and Uniprot Product Information

• NCBI GI #: 4505111
• NCBI GeneID: 4146
• NCBI Accession #: NP_002370.1
• NCBI GenBank Nucleotide #: NM_002379.3
• UniProt Accession #: P21941; Q5TBB9; B2R7E3
• Molecular Weight: Observed: 54 kDa; Predicted: 54 kDa
• NCBI Official Full Name: cartilage matrix protein
• NCBI Official Synonym Full Names: matrilin 1
• NCBI Official Symbol: MATN1
• NCBI Official Synonym Symbols: CMP; CRTM
• NCBI Protein Information: cartilage matrix protein
• UniProt Protein Name: Cartilage matrix protein
• Protein Family: Cartilage matrix protein
• UniProt Gene Name: MATN1
• UniProt Synonym Gene Names: CMP; CRTM

NCBI Description

This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. [provided by RefSeq, Jul 2008]

Uniprot Description

Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.