Immunohistochemistry (IHC)
(Formalin-paraffin human testis stained with MAGE-1 MAb (SPM282).)
Mouse MAGE-1 Monoclonal Antibody | anti-MAGE-1 antibody
MAGE-1 (MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma Associated antigen 1, Melanoma Associated antigen MZ2 E) (AP)
IHC: 0.5-1ug/ml for 30 minutes at RT
IF: 1-2ug/ml
WB: 0.5-1ug/ml
Applications are based on unconjugated antibody.
Immunohistochemistry (IHC)
(Formalin-paraffin human testis stained with MAGE-1 MAb (SPM282).)
Immunohistochemistry (IHC)
(Formalin-paraffin human testis stained with MAGE-1 MAb (SPM282).)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
Uniprot Description
MAGE-A1: a tumor antigen expressed in a variety of tumor cells and in the testis. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Protein type: Cell surface
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; histone deacetylase binding
Biological Process: transcription, DNA-dependent; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter
Research Articles on MAGE-1
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Product Notes
The MAGE-1 magea1 (Catalog #AAA6124336) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MAGE-1 (MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma Associated antigen 1, Melanoma Associated antigen MZ2 E) (AP) reacts with Canine, Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAGE-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). IP: 1-2ug/500ug protein lysate IHC: 0.5-1ug/ml for 30 minutes at RT IF: 1-2ug/ml WB: 0.5-1ug/ml Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MAGE-1 magea1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGE-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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