Typical Testing Data/Standard Curve (for reference only)
Mouse Tryptophan Hydroxylase 2 ELISA Kit | Tph2 elisa kit
Mouse Tryptophan Hydroxylase 2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
isoform of tryptophan hydroxylase; may play a role in seratonin biosynthesis [RGD, Feb 2006]
Uniprot Description
TPH2: an enzyme that is rate-limiting in the biosynthesis of serotonin. It catalyzes the biopterin dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Its expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells. Two alternatively spliced isoforms have been described. Isoform 2 appears to be expressed exclusively in the brain, and is expressed at significantly higher levels in the raphe nuclei than isoform 1.
Protein type: EC 1.14.16.4; Amino Acid Metabolism - tryptophan; Oxidoreductase
Cellular Component: neuron projection
Molecular Function: amino acid binding; tryptophan 5-monooxygenase activity; iron ion binding
Biological Process: circadian rhythm; response to nutrient levels; aromatic amino acid family metabolic process; response to estrogen stimulus; response to glucocorticoid stimulus; response to activity; response to calcium ion; serotonin biosynthetic process
Research Articles on Tph2
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Product Notes
The Mouse Tph2 tph2 (Catalog #AAA3807490) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3807490 ELISA Kit recognizes Mouse Tph2. It is sometimes possible for the material contained within the vial of "Tryptophan Hydroxylase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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