Testing Data
(Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta (MBS215696))
Rat LYMPHOTOXIN BETA RECEPTOR Monoclonal Antibody | anti-Ltbr antibody
RAT ANTI MOUSE LYMPHOTOXIN BETA RECEPTOR:Low Endotoxin
Gene Names
Ltbr; CD18; Ltar; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III
Applications
Flow Cytometry, Functional Assay, Functional Assay
Synonyms
LYMPHOTOXIN BETA RECEPTOR; Monoclonal Antibody; RAT ANTI MOUSE LYMPHOTOXIN BETA RECEPTOR:Low Endotoxin; anti-Ltbr antibody
Host
Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
5G11b
Form/Format
Low Endotoxin
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
415
Applicable Applications for anti-Ltbr antibody
Flow cytometry (FC/FACS), Functional Assays (FN)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Recombinant extracellular domain of LT beta R
Fusion Partners
Fusion Partners
Target Species
Mouse
Preparation and Storage
Store at -20 degree C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Testing Data
(Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta (MBS215696))
Testing Data
(Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta (MBS215696))
Testing Data
(Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta : FITC (MBS215693))
Testing Data
(Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta : FITC (MBS215693))
Related Product Information for anti-Ltbr antibody
Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes surface expressed LT beta R. Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlgans et al. 2003). Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is routinely tested on WEH1 cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,956 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 3
NCBI Official Synonym Full Names
lymphotoxin B receptor
NCBI Official Symbol
Ltbr
NCBI Official Synonym Symbols
CD18; Ltar; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III
NCBI Protein Information
tumor necrosis factor receptor superfamily member 3; LT beta-R; LT-beta receptor; TNF receptor-related protein; lymphotoxin-beta receptor; tumor necrosis factor receptor superfamily, member 3
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 3
Protein Family
UniProt Gene Name
Ltbr
UniProt Synonym Gene Names
Tnfcr; Tnfrsf3
UniProt Entry Name
TNR3_MOUSE
Uniprot Description
LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to membrane
Molecular Function: identical protein binding; protein binding; ubiquitin protein ligase binding
Biological Process: apoptosis; positive regulation of JNK cascade; myeloid dendritic cell differentiation; lymph node development
Research Articles on Ltbr
Similar Products
Product Notes
The Ltbr ltbr (Catalog #AAA215692) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LYMPHOTOXIN BETA RECEPTOR can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS), Functional Assays (FN). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100. Researchers should empirically determine the suitability of the Ltbr ltbr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LYMPHOTOXIN BETA RECEPTOR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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