Mouse anti-Human LSM16 Monoclonal Antibody | anti-LSM16 antibody

LSM16 (EDC3, YJDC, YJEFN2, Enhancer of mRNA-decapping Protein 3, LSM16 Homolog, YjeF N-terminal Domain-containing Protein 2, YjeF Domain-containing Protein 1, FLJ21128, FLJ31777) (AP)

Cat. Num. AAA6132155

• Gene Names: EDC3; YJDC; LSM16; YJEFN2
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LSM16; Monoclonal Antibody; LSM16 (EDC3; YJDC; YJEFN2; Enhancer of mRNA-decapping Protein 3; LSM16 Homolog; YjeF N-terminal Domain-containing Protein 2; YjeF Domain-containing Protein 1; FLJ21128; FLJ31777) (AP); anti-LSM16 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 4E3-3A4
• Specificity: Recognizes human LSM16.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-LSM16 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-509 from human LSM16 (AAH11534) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQHFGDLHQTELGPSGAGCQVGINQNGTGKFVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENVFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRIYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA
• Conjugate: AP
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (81.99kD).)

Western Blot (WB)

(FLJ21128 monoclonal antibody, Western Blot analysis of FLJ21128 expression in Hela NE.)

Western Blot (WB)

(Western Blot analysis of LSM16 expression in transfected 293T cell line by LSM16 monoclonal antibody. Lane 1: LSM16 transfected lysate (56kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-LSM16 antibody

Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.

Product Categories/Family for anti-LSM16 antibody

Antibodies; RNA Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 15079379
• NCBI GeneID: 80153
• Molecular Weight: 56,078 Da
• NCBI Official Full Name: Homo sapiens enhancer of mRNA decapping 3 homolog (S. cerevisiae), mRNA
• NCBI Official Synonym Full Names: enhancer of mRNA decapping 3
• NCBI Official Symbol: EDC3
• NCBI Official Synonym Symbols: YJDC; LSM16; YJEFN2
• NCBI Protein Information: enhancer of mRNA-decapping protein 3; LSM16 homolog (EDC3, S. cerevisiae); enhancer of mRNA decapping 3 homolog; hYjeF_N2; hYjeF_N2-15q23; yjeF N-terminal domain-containing protein 2; yjeF domain containing; yjeF domain-containing protein 1; yjeF_N2

NCBI Description

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008]