Western Blot (WB)
(Western Blot detection against Immunogen (37kD).)
Mouse anti-Human LRRN5 Monoclonal Antibody | anti-LRRN2 antibody
LRRN5 (Leucine-rich Repeat Neuronal Protein 2, Glioma Amplified on Chromosome 1 Protein, Leucine-rich Repeat Neuronal Protein 5, LRRN2, GAC1, UNQ256/PRO293)
Gene Names
LRRN2; GAC1; LRRN5; LRANK1; FIGLER7
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
LRRN5; Monoclonal Antibody; LRRN5 (Leucine-rich Repeat Neuronal Protein 2; Glioma Amplified on Chromosome 1 Protein; Leucine-rich Repeat Neuronal Protein 5; LRRN2; GAC1; UNQ256/PRO293); Anti -LRRN5 (Leucine-rich Repeat Neuronal Protein 2; anti-LRRN2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
6A9
Specificity
Recognizes human LRRN5.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
RVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRALGDRPG
Applicable Applications for anti-LRRN2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot and ELISA.
Immunogen
Partial recombinant corresponding to aa532-630 from LRRN5 (NP_006329) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (37kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (37kD).)
Western Blot (WB)
(Western Blot analysis of LRRN2 expression in transfected 293T cell line by LRRN5 monoclonal antibody.|Lane 1: LRRN2 transfected lysate (Predicted MW: 78.9kD).|Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of LRRN2 expression in transfected 293T cell line by LRRN5 monoclonal antibody.|Lane 1: LRRN2 transfected lysate (Predicted MW: 78.9kD).|Lane 2: Non-transfected lysate.)
Related Product Information for anti-LRRN2 antibody
LRRN5 (Leucine rich repeat neuronal 5) is a transmembrane protein belonging to the leucine-rich repeat (LRR) superfamily. It has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors. It is overexpressed in malignant gliomas.
Product Categories/Family for anti-LRRN2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78,859 Da
NCBI Official Full Name
leucine-rich repeat neuronal protein 2
NCBI Official Synonym Full Names
leucine rich repeat neuronal 2
NCBI Official Symbol
LRRN2
NCBI Official Synonym Symbols
GAC1; LRRN5; LRANK1; FIGLER7
NCBI Protein Information
leucine-rich repeat neuronal protein 2; leucine rich repeat neuronal 5; leucine rich and ankyrin repeats 1; leucine-rich repeat neuronal protein 5; glioma amplified on chromosome 1 protein; fibronectin type III, immunoglobulin and leucine rich repeat domain 7
UniProt Protein Name
Leucine-rich repeat neuronal protein 2
Protein Family
UniProt Gene Name
LRRN2
UniProt Synonym Gene Names
GAC1; LRRN5
UniProt Entry Name
LRRN2_HUMAN
NCBI Description
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
LRRN2:
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: integral to membrane
Molecular Function: receptor activity
Biological Process: signal transduction; cell adhesion
Research Articles on LRRN2
Similar Products
Product Notes
The LRRN2 lrrn2 (Catalog #AAA6009952) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LRRN5 (Leucine-rich Repeat Neuronal Protein 2, Glioma Amplified on Chromosome 1 Protein, Leucine-rich Repeat Neuronal Protein 5, LRRN2, GAC1, UNQ256/PRO293) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRN5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot and ELISA. Researchers should empirically determine the suitability of the LRRN2 lrrn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: RVQETHPYHI LLSWVTPPNT VSTNLTWSSA SSLRGQGATA LARLPRGTHS YNITRLLQAT EYWACLQVAF ADAHTQLACV WARTKEATSC HRALGDRPG. It is sometimes possible for the material contained within the vial of "LRRN5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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