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Western Blot (WB) (Western blot detection of LRRFIP1 in Raji,C2C12,MCF7&Jurkat cell lysates using LRRFIP1 antibody (1:1000 diluted). Predicted band size:89KDa. Observed band size:160KDa.)

Mouse LRRFIP1 Monoclonal Antibody | anti-LRRFIP1 antibody

Mouse monoclonal LRRFIP1 antibody

Gene Names
LRRFIP1; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
Applications
Western Blot
Synonyms
LRRFIP1; Monoclonal Antibody; Mouse monoclonal LRRFIP1 antibody; LRRFIP1 antibody; anti-LRRFIP1 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
M80554
Specificity
LRRFIP1 antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins
Form/Format
Supplied in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.2% sodium azide, 0.1% BSA and 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
752
Applicable Applications for anti-LRRFIP1 antibody
Western Blot (WB)
Immunogen
LRRFIP1 antibody was raised in Rabbit using a purified recombinant human LRRFIP1 protein fragments expressed in Ecoli as the immunogen
Cross-Reactivity
Human, Mouse
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage, store at -20 degree C.

Western Blot (WB)

(Western blot detection of LRRFIP1 in Raji,C2C12,MCF7&Jurkat cell lysates using LRRFIP1 antibody (1:1000 diluted). Predicted band size:89KDa. Observed band size:160KDa.)

Western Blot (WB) (Western blot detection of LRRFIP1 in Raji,C2C12,MCF7&Jurkat cell lysates using LRRFIP1 antibody (1:1000 diluted). Predicted band size:89KDa. Observed band size:160KDa.)
Product Categories/Family for anti-LRRFIP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
73,060 Da
NCBI Official Full Name
leucine-rich repeat flightless-interacting protein 1 isoform 5
NCBI Official Synonym Full Names
LRR binding FLII interacting protein 1
NCBI Official Symbol
LRRFIP1
NCBI Official Synonym Symbols
GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
NCBI Protein Information
leucine-rich repeat flightless-interacting protein 1
UniProt Protein Name
Leucine-rich repeat flightless-interacting protein 1
UniProt Gene Name
LRRFIP1
UniProt Synonym Gene Names
GCF2; TRIP; LRR FLII-interacting protein 1

Uniprot Description

LRRFIP1: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; RNA-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cell-cell adherens junction; cytoplasm; cytoskeleton; cytosol; plasma membrane

Molecular Function: DNA binding; double-stranded RNA binding; protein binding; protein homodimerization activity

Biological Process: positive regulation of interferon type I production; regulation of transcription from RNA polymerase II promoter

Research Articles on LRRFIP1

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Product Notes

The LRRFIP1 lrrfip1 (Catalog #AAA5306656) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LRRFIP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the LRRFIP1 lrrfip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRFIP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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