Mouse LRP Monoclonal Antibody | anti-LRP antibody
LRP antibody (515 kDa)
Reactivity
This antibody reacts with the 515 kDa a-chain of the Human LRP/a2MR which is expressed in a restricted spectrum of cell types
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
LRP; Monoclonal Antibody; LRP antibody (515 kDa); Monoclonal LRP (515 kDa); Anti-LRP (515 kDa); Low Density LPR; LPR/alpha 2MR; Anti LRP (515 kDa); LRP-515antibody; LPR515; Human Liporotein Receptor Related Protein; LRP (515 kDa); anti-LRP antibody
Host
Mouse
Reactivity
This antibody reacts with the 515 kDa a-chain of the Human LRP/a2MR which is expressed in a restricted spectrum of cell types
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8G1
Specificity
Human LRP
Form/Format
Lyophilized. Reconstitute in 1 ml distilled water (final solution contains 0.5% BSA in PBS buffer, pH 7.4)
Sequence Length
893
Applicable Applications for anti-LRP antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 1:20
Biological Significance
Lipoprotein receptor-related proteins are a group of human proteins. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91).
Cross-Reactivity
This antibody reacts with the 515 kDa a-chain of the human LRP/a2MR which is expressed in a restricted spectrum of cell types
Immunogen
LRP antibody (515 kDa) was raised in mouse using human LRP/a2MR as the immunogen.
Preparation and Storage
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles
Related Product Information for anti-LRP antibody
Mouse monoclonal LRP antibody (515 kDa)
Product Categories/Family for anti-LRP antibody
NCBI and Uniprot Product Information
Uniprot Description
MVP: Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: cytoskeleton; membrane; perinuclear region of cytoplasm; cytoplasm; nuclear pore; ribonucleoprotein complex; nucleus
Molecular Function: protein binding; protein phosphatase binding; protein kinase binding
Biological Process: cell proliferation; protein transport; mRNA transport; negative regulation of protein amino acid autophosphorylation
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Product Notes
The LRP mvp (Catalog #AAA531812) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LRP antibody (515 kDa) reacts with This antibody reacts with the 515 kDa a-chain of the Human LRP/a2MR which is expressed in a restricted spectrum of cell types and may cross-react with other species as described in the data sheet. AAA Biotech's LRP can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:20. Researchers should empirically determine the suitability of the LRP mvp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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