Mouse anti-Human Lipoproteins, High Density, Plasma Monoclonal Antibody
Lipoproteins, High Density, Plasma (High Density Lipoprotein 2, HDL 2, HDL2, High Density Lipoprotein 3, HDL 3, HDL3, Apolipoprotein A-I, Apo AI, Apo A-I, ApoA-I, Apo-AI, APOA1)
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Highly PurifiedPurified by sodium sulfate and DEAE-cellulose chromatography.
Synonyms
Lipoproteins; High Density; Plasma; Monoclonal Antibody; Plasma (High Density Lipoprotein 2; HDL 2; HDL2; High Density Lipoprotein 3; HDL 3; HDL3; Apolipoprotein A-I; Apo AI; Apo A-I; ApoA-I; Apo-AI; APOA1); Anti -Lipoproteins; anti-Lipoproteins; Plasma antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1C5
Specificity
Recognizes human high density lipoproteins (HDL 2, HDL 3, apo-A1) of human plasma. No crossreactions with other human plasma proteins were detected. Increases the specific binding of HDL to rat and human hepatocytes and the efflux of cholesterol from hepatocytes prelabelled with 14C-acetate.
Purity/Purification
Highly Purified
Purified by sodium sulfate and DEAE-cellulose chromatography.
Purified by sodium sulfate and DEAE-cellulose chromatography.
Form/Format
Supplied as a lyophilized powder from 10mM sodium phosphate, pH 8, 100mM sodium chloride, 1mM sodium azide, 0.1% mannitol. Reconstitute with 1ml sterile ddH2O.
Applicable Applications for anti-Lipoproteins, High Density, Plasma antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1000
Immunohistochemistry (Frozen): 1:100
Dilution: ELISA: 1:1000
Immunohistochemistry (Frozen): 1:100
Immunogen
Human HDL Apolipoprotein.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Lipoproteins, High Density, Plasma antibody
Apolipoprotein AI promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein AI is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77aa; an 18aa signal peptide is removed co-translationally and a 6aa propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Product Categories/Family for anti-Lipoproteins, High Density, Plasma antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
lipoprotein
Similar Products
Product Notes
The Lipoproteins, High Density, Plasma (Catalog #AAA631438) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Lipoproteins, High Density, Plasma (High Density Lipoprotein 2, HDL 2, HDL2, High Density Lipoprotein 3, HDL 3, HDL3, Apolipoprotein A-I, Apo AI, Apo A-I, ApoA-I, Apo-AI, APOA1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lipoproteins, High Density, Plasma can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: ELISA: 1:1000 Immunohistochemistry (Frozen): 1:100. Researchers should empirically determine the suitability of the Lipoproteins, High Density, Plasma for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lipoproteins, High Density, Plasma, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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