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Western Blot (WB) (Western Blot: Sample: Human Serum.)

Mouse anti-Human Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) Monoclonal Antibody | anti-LRG1 antibody

Monoclonal Antibody to Leucine Rich Alpha-2-Glycoprotein 1 (LRG1)

Gene Names
LRG1; LRG; HMFT1766
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G affinity chromatography
Synonyms
Leucine Rich Alpha-2-Glycoprotein 1 (LRG1); Monoclonal Antibody; Monoclonal Antibody to Leucine Rich Alpha-2-Glycoprotein 1 (LRG1); anti-LRG1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
C7
Specificity
The antibody is a mouse monoclonal antibody raised against LRG1. It has been selected for its ability to recognize LRG1 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G affinity chromatography
Form/Format
Liquid
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-LRG1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
Western Blot: 0.5-5ug/ml
Immunocytochemistry in formalin fixed cells: 5-30ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-30ug/ml
Immunohistochemistry in paraffin section: 5-30ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Immunogen
Recombinant Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) (Thr37~Leu340)
Cross Reactivity
Human
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Label
None
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2060746
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot: Sample: Human Serum.)

Western Blot (WB) (Western Blot: Sample: Human Serum.)

Western Blot (WB)

(Western Blot: Sample: Recombinant LRG1, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant LRG1, Human.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,178 Da
NCBI Official Full Name
leucine-rich alpha-2-glycoprotein
NCBI Official Synonym Full Names
leucine rich alpha-2-glycoprotein 1
NCBI Official Symbol
LRG1
NCBI Official Synonym Symbols
LRG; HMFT1766
NCBI Protein Information
leucine-rich alpha-2-glycoprotein
UniProt Protein Name
Leucine-rich alpha-2-glycoprotein
UniProt Gene Name
LRG1
UniProt Synonym Gene Names
LRG; LRG

NCBI Description

The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).[supplied by OMIM, Mar 2008]

Uniprot Description

LRG1:

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular region; extracellular space; intracellular membrane-bound organelle; membrane

Molecular Function: transforming growth factor beta receptor binding

Biological Process: brown fat cell differentiation; neutrophil degranulation; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; positive regulation of transforming growth factor beta receptor signaling pathway

Research Articles on LRG1

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Product Notes

The LRG1 lrg1 (Catalog #AAA2085912) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Western Blot: 0.5-5ug/ml Immunocytochemistry in formalin fixed cells: 5-30ug/ml Immunohistochemistry in formalin fixed frozen section: 5-30ug/ml Immunohistochemistry in paraffin section: 5-30ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Researchers should empirically determine the suitability of the LRG1 lrg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Leucine Rich Alpha-2-Glycoprotein 1 (LRG1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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