Mouse anti-Human LASP1 Monoclonal Antibody | anti-LASP1 antibody

LASP1 (LIM and SH3 Domain Protein 1, LASP-1, Metastatic Lymph Node Gene 50 Protein, MLN 50, MLN50) (FITC)

Cat. Num. AAA6147971

• Gene Names: LASP1; MLN50; Lasp-1
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LASP1; Monoclonal Antibody; LASP1 (LIM and SH3 Domain Protein 1; LASP-1; Metastatic Lymph Node Gene 50 Protein; MLN 50; MLN50) (FITC); anti-LASP1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 4F5
• Specificity: Recognizes human LASP1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).

• Applicable Applications for anti-LASP1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-262 from human LASP1 (AAH12460) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSRLQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAAYDYSAADEDAVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of LASP1 expression in transfected 293T cell line by LASP1 monoclonal antibody. Lane 1: LASP1 transfected lysate (29.7kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-LASP1 antibody

This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. [provided by RefSeq]

Product Categories/Family for anti-LASP1 antibody

Antibodies; Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 15214661
• NCBI GeneID: 3927
• Molecular Weight: 23,181 Da
• NCBI Official Full Name: Homo sapiens LIM and SH3 protein 1, mRNA
• NCBI Official Synonym Full Names: LIM and SH3 protein 1
• NCBI Official Symbol: LASP1
• NCBI Official Synonym Symbols: MLN50; Lasp-1
• NCBI Protein Information: LIM and SH3 domain protein 1
• Protein Family: LIM and SH3 domain protein

NCBI Description

This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]