Western Blot (WB)
(Western Blot analysis of MCF-7 cells using L2HGDH Monoclonal Antibody at dilution of 1:1000)
Mouse anti-Human L2HGDH Monoclonal Antibody | anti-L2HGDH antibody
L2HGDH Monoclonal Antibody
Gene Names
L2HGDH; L2HGA; C14orf160
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein A purification
Synonyms
L2HGDH; Monoclonal Antibody; L2HGDH Monoclonal Antibody; 2 hydroxyglutarate dehydrogenase; Alpha hydroxyglutarate oxidoreductase; Alpha ketoglutarate reductase; C14orf160; Duranin; FLJ12618; L alpha hydroxyglutarate dehydrogenase; L-2-hydroxyglutarate dehydrogenase; mitochondrial; L2HDH; l2hgdh; anti-L2HGDH antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
123
Purity/Purification
Protein A purification
Concentration
1mg/mL (varies by lot)
Sequence Length
463
Applicable Applications for anti-L2HGDH antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:5000
IHC: 1:100-1:400
IHC: 1:100-1:400
Immunogen
Fusion protein of L2HGDH
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of MCF-7 cells using L2HGDH Monoclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of MCF-7 cells using L2HGDH Monoclonal Antibody at dilution of 1:1000)
Related Product Information for anti-L2HGDH antibody
2HGDH(L-2-hydroxyglutarate dehydrogenase, mitochondrial) is also named as duranin, C14orf160 and belongs to the L2HGDH family.T he putative L2HGDH is predicted to be targeted to the mitochondria where its mitochondrial targeting sequence is presumably removed. Defects in L2HGDH are the cause of L-2-hydroxyglutaric aciduria (L2HGA).
Product Categories/Family for anti-L2HGDH antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 50kDa; 49kDa
Observed: 45kDa
Observed: 45kDa
NCBI Official Full Name
L-2-hydroxyglutarate dehydrogenase, mitochondrial
NCBI Official Synonym Full Names
L-2-hydroxyglutarate dehydrogenase
NCBI Official Symbol
L2HGDH
NCBI Official Synonym Symbols
L2HGA; C14orf160
NCBI Protein Information
L-2-hydroxyglutarate dehydrogenase, mitochondrial
UniProt Protein Name
L-2-hydroxyglutarate dehydrogenase, mitochondrial
UniProt Gene Name
L2HGDH
UniProt Synonym Gene Names
C14orf160
NCBI Description
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]
Uniprot Description
MiscellaneousWas named 'duranin' in honor of Marinus Duran, who first described L-2-hydroxyglutaric aciduria.
Research Articles on L2HGDH
Similar Products
Product Notes
The L2HGDH l2hgdh (Catalog #AAA2542202) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The L2HGDH Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's L2HGDH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:5000 IHC: 1:100-1:400. Researchers should empirically determine the suitability of the L2HGDH l2hgdh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L2HGDH, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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