Mouse L-Afadin Monoclonal Antibody | anti-Mllt4 antibody
L-Afadin, Rat, mAb 3
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
NCBI and Uniprot Product Information
NCBI Description
may play a role in linking the actin cytoskeleton to the plasma membrane [RGD, Feb 2006]
Uniprot Description
Afadin: plays a role in adhesion by participating, along with E-cadherin and catenin, in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Essential for the association of nectin and E-cadherin. Contains 1 forkhead-associated (FHA) domain, a phosphopeptide recognition domain; 1 dilute (DIL) domain, a myosin-like domain which may play a functional role in cellular processes or vectorial vesicle transport; 1 PDZ domain, which frequently binds the carboxyl-terminal sequences of proteins or phosphatidylinositol 4,5-bisphosphate in the plasma membrane; and 2 RA domains, which are associated with RasGTP effector activity. Five alternatively spliced isoforms have been described. Isoform 2 does not interact with F-actin.
Protein type: Oncoprotein; Cell adhesion; Motility/polarity/chemotaxis
Cellular Component: nucleoplasm; adherens junction; cell-cell adherens junction; apical part of cell; cytoplasm; plasma membrane; intercellular junction; nucleus; cytosol; cell junction
Molecular Function: protein binding; LIM domain binding; Ras GTPase binding; cell adhesion molecule binding
Biological Process: cell adhesion; signal transduction
Research Articles on Mllt4
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Product Notes
The Mllt4 mllt4 (Catalog #AAA584288) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The L-Afadin, Rat, mAb 3 reacts with Reactivity: Rat. Cross reactivity: Canine, Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's L-Afadin can be used in a range of immunoassay formats including, but not limited to, F, Immunoassay (IA), Immunoprecipitation (IP), Western Blot (WB). Application Use: For Western blot and immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Fixation with PFA or acetone/methanol is recommended. Researchers should empirically determine the suitability of the Mllt4 mllt4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L-Afadin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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