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Mouse Krueppel-like factor 7 Monoclonal Antibody | anti-KLF7 antibody

Mouse Anti Human Krueppel-like factor 7

Gene Names
KLF7; UKLF
Applications
ELISA, Western Blot
Purity
KLF7 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Synonyms
Krueppel-like factor 7; Monoclonal Antibody; Mouse Anti Human Krueppel-like factor 7; KLF7 Antibody; Mouse Anti Human; UKLF; Ubiquitous krueppel-like factor; KLF7; anti-KLF7 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1 heavy chain and Kappa light chain
Clone Number
PAT3G3A
Purity/Purification
KLF7 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile filtered colorless solution.
Sequence Length
274
Applicable Applications for anti-KLF7 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Immunogen
Anti-human KLF7 mAb, clone PAT3G3A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KLF7 protein 1-302 amino acids purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-KLF7 antibody
Introduction: Kruppel-Like Factor 7 (KLF7) is a part of the Kruppel-like transcriptional regulator family whose members regulate cell proliferation, differentiation and survival and contain 3 C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 contributes to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and also by deregulating adipocytokine secretion in adipocytes.
Product Categories/Family for anti-KLF7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
9,295 Da
NCBI Official Full Name
Krueppel-like factor 7 isoform 4
NCBI Official Synonym Full Names
Kruppel-like factor 7 (ubiquitous)
NCBI Official Symbol
KLF7
NCBI Official Synonym Symbols
UKLF
NCBI Protein Information
Krueppel-like factor 7; ubiquitous Kruppel-like transcription factor
UniProt Protein Name
Krueppel-like factor 7
Protein Family
UniProt Gene Name
KLF7
UniProt Synonym Gene Names
UKLF
UniProt Entry Name
KLF7_HUMAN

NCBI Description

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Description

KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: nucleus

Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; dendrite morphogenesis; positive regulation of transcription, DNA-dependent

Research Articles on KLF7

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Product Notes

The KLF7 klf7 (Catalog #AAA140457) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Krueppel-like factor 7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000. Researchers should empirically determine the suitability of the KLF7 klf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Krueppel-like factor 7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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