Mouse anti-Human KIF26A Monoclonal Antibody | anti-KIF26A antibody

KIF26A (Kinesin Family Member 26A, Kinesin-like Protein KIF26A, DKFZP434N178, FLJ22753, KIAA1236)

Cat. Num. AAA6011782

• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: KIF26A; Monoclonal Antibody; KIF26A (Kinesin Family Member 26A; Kinesin-like Protein KIF26A; DKFZP434N178; FLJ22753; KIAA1236); Anti -KIF26A (Kinesin Family Member 26A; anti-KIF26A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 3C10
• Specificity: Recognizes human KIF26A.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MSESGAASPGARTRSLKSPKKRATGLQRRRLIPAPLPDTTALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRPRPTPREAPTQGLACVSTRLRLAERRQQRLREVQAKHKHLCEELAETQGRLMLEPGRWLEQFEVDPELEPESAEYLAALERATAALEQCVNLCKAHVMMVTCFDISVAASAAIPGPQEVDV*

• Applicable Applications for anti-KIF26A antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.
• Immunogen: Full length recombinant protein corresponding to aa1-204, from human KIF26A (AAH09415). MW of the GST tag alone is 26kD.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (48.44kD).)

Western Blot (WB)

(KIF26A monoclonal antibody Western Blot analysis of KIF26A expression in HeLa.)

Testing Data

(Detection limit for recombinant GST tagged KIF26A is ~0.3ng/ml as a capture antibody.)

Related Product Information for anti-KIF26A antibody

Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity.

Product Categories/Family for anti-KIF26A antibody

Antibodies; Abs to Motor Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 150170699
• NCBI GeneID: 26153
• NCBI Accession #: NP_056471.1
• NCBI GenBank Nucleotide #: NM_015656.1
• UniProt Accession #: Q9ULI4; Q8TAZ7; Q96GK3; Q9UFL3
• Molecular Weight: 194,590 Da
• NCBI Official Full Name: kinesin-like protein KIF26A
• NCBI Official Synonym Full Names: kinesin family member 26A
• NCBI Official Symbol: KIF26A
• NCBI Protein Information: kinesin-like protein KIF26A; KIF26A variant protein
• UniProt Protein Name: Kinesin-like protein KIF26A
• Protein Family: Kinesin-like protein
• UniProt Gene Name: KIF26A
• UniProt Synonym Gene Names: KIAA1236
• UniProt Entry Name: KI26A_HUMAN

Uniprot Description

KIF26A: Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity. Belongs to the kinesin-like protein family. KIF26 subfamily.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: microtubule; kinesin complex; cytosol

Molecular Function: microtubule binding; ATPase activity; microtubule motor activity; ATP binding

Biological Process: regulation of cell growth by extracellular stimulus; metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; enteric nervous system development; microtubule-based movement; negative regulation of signal transduction