Mouse Keratin K5/K8 Monoclonal Antibody
Keratin K5/K8 Pan Epithelial antibody
Applications
Immunohistochemistry, Western Blot
Purity
Keratin K5/K8 (Pan Epithelial) antibody was purified by Protein A affinity chromatography
Synonyms
Keratin K5/K8; Monoclonal Antibody; Keratin K5/K8 Pan Epithelial antibody; Monoclonal Keratin K5/K8 Pan Epithelial; Anti Keratin K5/K8 Pan Epithelial; Keratin K/K8-5; Keratin K/K8 5; Cytokeratin 5/8 Pan Epithelial; anti-Keratin K5/K8 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
C22
Specificity
Human keratin K8
Purity/Purification
Keratin K5/K8 (Pan Epithelial) antibody was purified by Protein A affinity chromatography
Form/Format
Supplied in liquid form, contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4
Applicable Applications for anti-Keratin K5/K8 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Biological Significance
Keratin K5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. The type II cytokeratin genes are clustered in a region of chromosome 12q12-q13. Keratin K8 is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to CK8 can be used to differentiate lobular carcinoma of the breast from ductal carcinoma of the breast. Keratin 8 is often used together with keratin 18 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Cross-Reactivity
Bovine, Murine, Amphibia, Pig, Fish
Immunogen
Keratin K5/K8 (Pan Epithelial) antibody was raised in mouse using human keratin K8, purified from SDS PAGE gel as the immunogen.
Preparation and Storage
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-Keratin K5/K8 antibody
Mouse monoclonal Keratin K5/K8 (Pan Epithelial) antibody
Product Categories/Family for anti-Keratin K5/K8 antibody
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Product Notes
The Keratin K5/K8 (Catalog #AAA533446) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Keratin K5/K8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the Keratin K5/K8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Keratin K5/K8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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