Mouse anti-Human ITGAX/CD11c Monoclonal Antibody | anti-ITGAX/CD11c antibody

ITGAX/CD11c, NT (ITGAX, CD11C, Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, CD_antigen=CD11c) (Biotin)

Cat. Num. AAA6121195

• Gene Names: ITGAX; CD11C; SLEB6
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein G Affinity Chromatography
• Synonyms: ITGAX/CD11c; Monoclonal Antibody; NT (ITGAX; CD11C; Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150; 95 alpha chain; Leukocyte adhesion receptor p150; 95; CD_antigen=CD11c) (Biotin); ITGAX; CD_antigen=CD11c; Flags: Precursor; anti-ITGAX/CD11c antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 428CT12.2.6.4
• Purity/Purification: Purified by Protein G Affinity Chromatography
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-ITGAX/CD11c antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: ITGAX/CD11c Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the N-term region of human ITGAX/CD11c.
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ITGAX/CD11c Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ITGAX/CD11c antibody detected the ITGAX/CD11c protein (arrow).)

Related Product Information for anti-ITGAX/CD11c antibody

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Product Categories/Family for anti-ITGAX/CD11c antibody

Antibodies; CD Markers

References

Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(33):14727-14732(2010) Lindsay, R.W., et al. J. Immunol. 185(3):1513-1521(2010) Kraus, T.S., et al. Am. J. Clin. Pathol. 134(2):271-277(2010) Quist, S.R., et al. Acta Derm. Venereol. 90(4):429-430(2010)

NCBI and Uniprot Product Information

• NCBI GI #: 34452173
• NCBI GeneID: 3687
• NCBI Accession #: NP_000878.2
• NCBI GenBank Nucleotide #: NM_000887.3
• UniProt Accession #: P20702; Q8IVA6
• Molecular Weight: 150kDa
• NCBI Official Full Name: integrin alpha-X
• NCBI Official Synonym Full Names: integrin, alpha X (complement component 3 receptor 4 subunit)
• NCBI Official Symbol: ITGAX
• NCBI Official Synonym Symbols: CD11C; SLEB6
• NCBI Protein Information: integrin alpha-X; leu M5, alpha subunit; p150 95 integrin alpha chain; CD11 antigen-like family member C; leukocyte adhesion receptor p150,95; myeloid membrane antigen, alpha subunit; leukocyte surface antigen p150,95, alpha subunit; leukocyte adhesion gl
• UniProt Protein Name: Integrin alpha-X
• UniProt Gene Name: ITGAX
• UniProt Synonym Gene Names: CD11C
• UniProt Entry Name: ITAX_HUMAN