Mouse Interleukin 6 Receptor, gp80, non-neutralizing Monoclonal Antibody
Interleukin 6 Receptor, gp80, non-neutralizing (CD126, IL-6R)
Applications
ELISA, Flow Cytometry
Purity
Purified
Synonyms
Interleukin 6 Receptor; gp80; non-neutralizing; Monoclonal Antibody; non-neutralizing (CD126; IL-6R); Anti -Interleukin 6 Receptor; anti-Interleukin 6 Receptor; non-neutralizing antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
2B2.3
Specificity
Recognizes soluble and membrane bound human IL-6 receptor gp80. Binds to the IL-6 receptor in the presence of IL-6.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS. No preservatives added.
Concentration
4mg/mL (varies by lot)
Applicable Applications for anti-Interleukin 6 Receptor, gp80, non-neutralizing antibody
ELISA (EIA), Flow Cytometry (FC)
Application Notes
Other applications have not been tested.
Optimal dilutions should be determined by the researcher.
Optimal dilutions should be determined by the researcher.
Immunogen
CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
Hybridoma
(IFFa Credo)/X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Interleukin 6 Receptor, gp80, non-neutralizing antibody
The IL-6 receptor system consists of two chains, IL-6R alpha and gp130. The IL-6R alpha is the binding component speci c to the IL-6, but does not transduce a signal alone. On the contrary, gp130 transmits signals not only of IL-6, but also IL-6 related cytokines, i.e. LIF, OSM, CNTF, IL-11 and CT-1. The low af nity binding sites for IL-6, is composed of IL-6R alpha alone. At low concentrations, soluble IL-6R alpha acts as an agonist of IL-6 activity.
Product Categories/Family for anti-Interleukin 6 Receptor, gp80, non-neutralizing antibody
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Product Notes
The Interleukin 6 Receptor, gp80, non-neutralizing (Catalog #AAA603039) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Interleukin 6 Receptor, gp80, non-neutralizing can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC). Other applications have not been tested. Optimal dilutions should be determined by the researcher. Researchers should empirically determine the suitability of the Interleukin 6 Receptor, gp80, non-neutralizing for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin 6 Receptor, gp80, non-neutralizing, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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