SDS-Page
(SDS-PAGE Analysis. Purified IRF9 Mouse Monoclonal Antibody (PCRP-IRF9-2F8). Confirmation of Purity and Integrity of Antibody. )
Mouse anti-Human Interferon regulatory factor 9/IRF-9 Monoclonal Antibody | anti-IRF9 antibody
Interferon regulatory factor 9/IRF-9 Mouse Monoclonal Antibody [Clone PCRP-IRF9-2F8]
Gene Names
IRF9; p48; IRF-9; ISGF3; ISGF3G
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunofluorescence
Synonyms
Interferon regulatory factor 9/IRF-9; Monoclonal Antibody; Interferon regulatory factor 9/IRF-9 Mouse Monoclonal Antibody [Clone PCRP-IRF9-2F8]; IFN alpha responsive transcription factor subunit; Interferon regulatory factor 9; Interferon-stimulated gene factor 3 gamma; interferon-stimulated transcription factor 3; gamma 48kDa; IRF-9; ISGF-3 gamma; ISGF3 p48 subunit; ISGF3G; p48; Transcriptional regulator ISGF3 subunit gamma; anti-IRF9 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2a
Clone Number
PCRP-IRF9-2F8
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-IRF9 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes
FC/FACS: 1-2ug/million cells
IF: 1-2ug/ml
IF: 1-2ug/ml
Immunogen
Recombinant full-length human IRF9 protein
Cellular Localization
Cytoplasm, Nucleus, Translocated into the nucleus upon activation by IFN-alpha/beta
Positive Control
MCF-7, Jurkat or K562 cells.
Hu-chromosome Location
14q12
Unigene
1706
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-Page
(SDS-PAGE Analysis. Purified IRF9 Mouse Monoclonal Antibody (PCRP-IRF9-2F8). Confirmation of Purity and Integrity of Antibody. )
SDS-Page
(SDS-PAGE Analysis. Purified IRF9 Mouse Monoclonal Antibody (PCRP-IRF9-2F8). Confirmation of Purity and Integrity of Antibody. )
Related Product Information for anti-IRF9 antibody
Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
393
NCBI Official Full Name
Interferon regulatory factor 9
NCBI Official Synonym Full Names
interferon regulatory factor 9
NCBI Official Symbol
IRF9
NCBI Official Synonym Symbols
p48; IRF-9; ISGF3; ISGF3G
NCBI Protein Information
interferon regulatory factor 9; ISGF-3 gamma; ISGF3 p48 subunit; interferon-stimulated gene factor 3 gamma; transcriptional regulator ISGF3 subunit gamma; IFN-alpha-responsive transcription factor subunit; interferon-stimulated transcription factor 3, gam
UniProt Protein Name
Interferon regulatory factor 9
Protein Family
UniProt Gene Name
IRF9
UniProt Synonym Gene Names
ISGF3G; IRF-9; ISGF-3 gamma
UniProt Entry Name
IRF9_HUMAN
Uniprot Description
IRF9: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. Belongs to the IRF family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus
Molecular Function: protein binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; cell surface receptor linked signal transduction; regulation of transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; interferon type I biosynthetic process; defense response to virus
Research Articles on IRF9
Similar Products
Product Notes
The IRF9 irf9 (Catalog #AAA4381743) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Interferon regulatory factor 9/IRF-9 Mouse Monoclonal Antibody [Clone PCRP-IRF9-2F8] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Interferon regulatory factor 9/IRF-9 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF). FC/FACS: 1-2ug/million cells IF: 1-2ug/ml. Researchers should empirically determine the suitability of the IRF9 irf9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interferon regulatory factor 9/IRF-9, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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