Rabbit anti-Mouse IL13RA1 Monoclonal Antibody | anti-IL13Ra1 antibody
Recombinant Anti-IL13RA1 Antibody, Rabbit Monoclonal
Reactivity
Mouse
Applications
ELISA, ELISA
Purity
Protein A
Synonyms
IL13RA1; Monoclonal Antibody; Recombinant Anti-IL13RA1 Antibody; Rabbit Monoclonal; IL13RA1/CD213A1 Antibody; Rabbit MAb; interleukin 13 receptor; alpha 1; Anti-AI882074 Antibody; Anti-CD213a1 Antibody; Anti-IL-13r[a] Antibody; Anti-Il13ra Antibody; Anti-NR4 Antibody; anti-IL13Ra1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
122
Specificity
Mouse IL13RA1/CD213A1.
No cross-reactivity in ELISA with Human IL13RA1/CD213A1, Mouse IL13RA2/CD213A2
No cross-reactivity in ELISA with Human IL13RA1/CD213A1, Mouse IL13RA2/CD213A2
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-IL13Ra1 antibody
ELISA (EIA), ELISA (EIA) (Det)
Application Notes
ELISA: 1:5000-1:10,000
ELISA (Det): 1:1000-1:10,000
ELISA (Det): This antibody will detect Mouse IL13RA1/IL-13RA1 in ELISA pair set.
In a sandwich ELISA, it can be used as detection antibody when paired with.
ELISA (Det): 1:1000-1:10,000
ELISA (Det): This antibody will detect Mouse IL13RA1/IL-13RA1 in ELISA pair set.
In a sandwich ELISA, it can be used as detection antibody when paired with.
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse IL13RA1 protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL13RA1 (rM IL13RA1).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-IL13Ra1 antibody
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Product Categories/Family for anti-IL13Ra1 antibody
References
Kawakami M, et al. (2002) Mutation and functional analysis of IL-13 receptors in human malignant glioma cells. Oncol Res. 12 (11-12): 459-67.Umeshita-Suyama R, et al. (2000) Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: redundancy of requirement of tyrosine residue for STAT3 activation. Int Immunol. 12 (11): 1499-509.He JQ, et al. (2003) Polymorphisms in the IL13, IL13RA1, and IL4RA genes and rate of decline in lung function in smokers. Am J Respir. Cell Mol Biol. 28 (3): 379-85.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,402 Da
NCBI Official Full Name
interleukin-13 receptor subunit alpha-1
UniProt Protein Name
Interleukin-13 receptor subunit alpha-1
Protein Family
UniProt Gene Name
Il13ra1
UniProt Synonym Gene Names
Il13r; Il13ra; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; NR4
UniProt Entry Name
I13R1_MOUSE
NCBI Description
This gene encodes a transmembrane protein that complexes with interleukin 4 receptor alpha (IL4RA) to form a functional receptor for interleukin-13. Signalling through this pathway mediates allergy response and occurs during bronchial asthma. [provided by RefSeq, May 2015]
Uniprot Description
IL13R: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. Belongs to the type I cytokine receptor family. Type 5 subfamily.
Protein type: Receptor, cytokine; Membrane protein, integral
Cellular Component: membrane; integral to membrane
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-13 receptor activity
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Product Notes
The IL13Ra1 il13ra1 (Catalog #AAA8110954) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-IL13RA1 Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL13RA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), ELISA (EIA) (Det). ELISA: 1:5000-1:10,000 ELISA (Det): 1:1000-1:10,000 ELISA (Det): This antibody will detect Mouse IL13RA1/IL-13RA1 in ELISA pair set. In a sandwich ELISA, it can be used as detection antibody when paired with. Researchers should empirically determine the suitability of the IL13Ra1 il13ra1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL13RA1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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