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Mouse IL-8 Monoclonal Antibody | anti-IL-8 antibody

Biotin conjugated mAb anti-Human IL-8

Gene Names
CXCL8; IL8
Reactivity
Human. Other species not tested
This antibody does not cross react with human Monocyte Chemotactic Activating Factor (MCAF) or RANTES (Regulated on Activation, Normal T-cell Expressed, and Secreted).
Applications
ELISA, ELISA
Purity
Protein G affinity purified
Synonyms
IL-8; Monoclonal Antibody; Biotin conjugated mAb anti-Human IL-8; Interleukin-8 (IL-8) (**Biotin Labeled); Biotin conjugated mouse monoclonal antibody to human interleukin 8 (IL-8); anti-IL-8 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human. Other species not tested
This antibody does not cross react with human Monocyte Chemotactic Activating Factor (MCAF) or RANTES (Regulated on Activation, Normal T-cell Expressed, and Secreted).
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
I8-60
Specificity
THis antibody recognizes both recombinant and native human IL-8.
Purity/Purification
Protein G affinity purified
Form/Format
0.01M PBS, pH 7.2 in 1% gelatin and 0.1% proclin-300
Sequence Length
101
Applicable Applications for anti-IL-8 antibody
ELISA: In combination with a monoclonal capture antibody and avidin-HRP conjugate, this biotin conjugated antibody can be used as a tracer antibody in sandwich ELISA applications for human IL-8 detection.
Application Notes
ELISA: In combination with a monoclonal capture antibody and avidin-HRP conjugate, this biotin conjugated antibody can be used as a tracer antibody in sandwich ELISA applications for human IL-8 detection.
Working Condition: 1:1000
Target Protein
Human IL-8
Immunogen
Purified recombinant human IL-8
Myeloma
P3X63Ag8.653
Light Chain
Kappa
Product type
Tracer Antibody in matched antibody pair, biotin conjugated.
Research Area
Cytokine, interleukin and chemotaxis
Intended Uses
Tracer**
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-IL-8 antibody
Biotin conjugated mouse monoclonal antibody to human interleukin 8 (IL-8)
Background: Interleukin 8 (IL-8), like IL-6, is secreted by macrophages and a variety of cell sthat express Toll-like receptors in response to the stimulation of pathogens. IL-8's primary function is to recruit neutrophils and other target cells through chemotaxis to the infected site to eliminate pathogens. IL-8 causes increased intracellular Ca2+, release of reactive oxygen species, and other physiological changes required for migration and phagocytosis. IL-8 is also known to promote angiogenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
interleukin-8
NCBI Official Symbol
CXCL8
NCBI Official Synonym Symbols
IL8
NCBI Protein Information
interleukin-8; C-X-C motif chemokine 8; IL-8; chemokine (C-X-C motif) ligand 8
UniProt Protein Name
Interleukin-8
UniProt Gene Name
CXCL8
UniProt Entry Name
IL8_MACMU

Uniprot Description

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus ().

Research Articles on IL-8

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Product Notes

The IL-8 cxcl8 (Catalog #AAA592055) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Biotin conjugated mAb anti-Human IL-8 reacts with Human. Other species not tested This antibody does not cross react with human Monocyte Chemotactic Activating Factor (MCAF) or RANTES (Regulated on Activation, Normal T-cell Expressed, and Secreted). and may cross-react with other species as described in the data sheet. AAA Biotech's IL-8 can be used in a range of immunoassay formats including, but not limited to, ELISA: In combination with a monoclonal capture antibody and avidin-HRP conjugate, this biotin conjugated antibody can be used as a tracer antibody in sandwich ELISA applications for human IL-8 detection. ELISA: In combination with a monoclonal capture antibody and avidin-HRP conjugate, this biotin conjugated antibody can be used as a tracer antibody in sandwich ELISA applications for human IL-8 detection. Working Condition: 1:1000. Researchers should empirically determine the suitability of the IL-8 cxcl8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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