Rat IL-2 Monoclonal Antibody | anti-Il2 antibody
RAT ANTI MOUSE INTERLEUKIN-2
Purified IgG - liquid
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/50; Application Note: Membrane permeabilization is required for this application. MyBioSource recommends the use of Leucoperm for this purpose.
Preparation
Fusion Partners
Shelf Life: 18 months from date of despatch.
NCBI and Uniprot Product Information
Uniprot Description
IL2: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Belongs to the IL-2 family.
Protein type: Secreted; Secreted, signal peptide; Oncoprotein; Cytokine
Cellular Component: extracellular space; cell; extracellular region; cytosol
Molecular Function: growth factor activity; interleukin-2 receptor binding; cytokine activity; glycosphingolipid binding; carbohydrate binding; kappa-type opioid receptor binding
Biological Process: positive regulation of interleukin-17 production; positive regulation of isotype switching to IgG isotypes; regulation of T cell homeostatic proliferation; positive regulation of regulatory T cell differentiation; negative regulation of heart contraction; immune system process; positive regulation of immunoglobulin secretion; positive regulation of activated T cell proliferation; negative regulation of lymphocyte proliferation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of interferon-gamma production; positive regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of protein amino acid phosphorylation; positive regulation of T cell differentiation; negative regulation of inflammatory response; protein kinase C activation; positive regulation of B cell proliferation; immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of T cell proliferation; positive regulation of protein amino acid phosphorylation; negative regulation of B cell apoptosis
Research Articles on Il2
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Product Notes
The Il2 il2 (Catalog #AAA212083) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow cytometry (FC/FACS)*, Immunoprecipitation (IP). Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/50; Application Note: Membrane permeabilization is required for this application. MyBioSource recommends the use of Leucoperm for this purpose. Researchers should empirically determine the suitability of the Il2 il2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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