Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant IGJ protein (Right) or empty vector (Left) detected with IGJ antibody)
Mouse IGJ Monoclonal Antibody | anti-IGJ antibody
IGJ antibody
Gene Names
JCHAIN; IGJ; JCH; IGCJ
Applications
Immunohistochemistry, Western Blot
Purity
IGJ antibody was purified by affinity chromatography.
Synonyms
IGJ; Monoclonal Antibody; IGJ antibody; Monoclonal IGJ; Anti-IGJ; Immunoglobulin J polypeptide; IGCJ; JCH; Immunoglobulin J chain; anti-IGJ antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3B3
Purity/Purification
IGJ antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
159
Applicable Applications for anti-IGJ antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 1:150
WB: 1:2000
WB: 1:2000
Biological Significance
IGJ serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Cross-Reactivity
Human
Immunogen
IGJ antibody was raised in mouse using a full length recombinant protein of human IGJ (NP_653247) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant IGJ protein (Right) or empty vector (Left) detected with IGJ antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant IGJ protein (Right) or empty vector (Left) detected with IGJ antibody)
Related Product Information for anti-IGJ antibody
Mouse monoclonal IGJ antibody
Product Categories/Family for anti-IGJ antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,099 Da
NCBI Official Full Name
immunoglobulin J chain
NCBI Official Synonym Full Names
joining chain of multimeric IgA and IgM
NCBI Official Symbol
JCHAIN
NCBI Official Synonym Symbols
IGJ; JCH; IGCJ
NCBI Protein Information
immunoglobulin J chain
UniProt Protein Name
Immunoglobulin J chain
UniProt Gene Name
IGJ
UniProt Synonym Gene Names
IGCJ
UniProt Entry Name
IGJ_HUMAN
Uniprot Description
IGJ: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular space; extracellular region
Molecular Function: peptidoglycan binding; protein homodimerization activity; IgA binding; phosphatidylcholine binding; antigen binding; single-stranded DNA binding
Biological Process: retinal homeostasis; positive regulation of protein oligomerization; adaptive immune response; glomerular filtration; antibacterial humoral response; innate immune response; immune response
Research Articles on IGJ
Similar Products
Product Notes
The IGJ igj (Catalog #AAA838157) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IGJ can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:150 WB: 1:2000. Researchers should empirically determine the suitability of the IGJ igj for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGJ, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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