IgA secondary antibody
IgA, Secretory Component (APC)
Gene Names
IGHA1; IgA1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
IgA; Monoclonal Secondary Antibody; Secretory Component (APC); IgA secondary antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2259
Specificity
Recognizes human secretory-piece and secretory IgA. No reaction against myeloma IgA (native or reduced and alkylated). Negative against normal human IgM, myeloma IgM, normal human IgG; free kappa or gamma chains and J-chain. Typical pattern on frozen and paraffin embedded sections of intestinal and breast tissue.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Applicable Applications for IgA secondary antibody
FLISA, Immunohistochemistry (IHC)
Conjugate
APC
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for IgA secondary antibody
References
1. Baldas, V. et al. (2004) Testing for anti-human transglutaminase antibodies in saliva is not useful for diagnosis of celiac disease. Clin Chem. 50: 216-9.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
160,000
NCBI Official Full Name
Ig alpha-1 chain C region
NCBI Official Synonym Full Names
immunoglobulin heavy constant alpha 1
NCBI Official Symbol
IGHA1
NCBI Official Synonym Symbols
IgA1
UniProt Protein Name
Ig alpha-1 chain C region
Protein Family
UniProt Gene Name
IGHA1
UniProt Entry Name
IGHA1_HUMAN
Uniprot Description
IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
Protein type: Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: antigen binding
Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
Research Articles on IgA
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Product Notes
The IgA igha1 (Catalog #AAA6268860) is a Secondary Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IgA, Secretory Component (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IgA can be used in a range of immunoassay formats including, but not limited to, FLISA, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the IgA igha1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgA, Monoclonal Secondary Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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