Mouse anti-Human IFN-g Monoclonal Antibody | anti-IFNg antibody
Mouse Anti-Human IFNg Detection Antibody, Biotin Conjugated Clone B-G1
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015]
Uniprot Description
Function: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Subunit structure: Homodimer.
Subcellular location: Secreted.
Tissue specificity: Released primarily from activated T lymphocytes.
Sequence similarities: Belongs to the type II (or gamma) interferon family.
Research Articles on IFNg
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Product Notes
The IFNg ifng (Catalog #AAA335002) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human IFNg Detection Antibody, Biotin Conjugated Clone B-G1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IFN-g can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), ELISpot (ES). ELISA Detection Antibody. This Antibody can be used as Detection in a human IFN-g sandwich Immunoassay to detect human IFN-g in combination with human IFN-g Capture Antibody (Cat n degree879.000.001). The suggested coating concentration range below should be optimised by each laboratory for each application. Researchers should empirically determine the suitability of the IFNg ifng for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFN-g, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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