Mouse anti-Human IFN-alpha Monoclonal Antibody | anti-IFN-alpha antibody
Mouse Anti-Human IFN-alpha
Reactivity
Human
Purity
Protein A chromatography
Synonyms
IFN-alpha; Monoclonal Antibody; Mouse Anti-Human IFN-alpha; Monoclonal antibody anti-human IFN-; anti-IFN-alpha antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Purity/Purification
Protein A chromatography
Form/Format
Lyophilized
Sequence Length
190
Application Notes
ELISA: This antibody can be used at a concentration of 1-2 ug/ml, as a capture antibody in conjunction with a compatible secondary reagent to yield satisfactory results in a sandwich ELISA.
Antibody Generation
Monoclonal antibodies were produced in BALB/c x ICR F1 mice using recombinant human IFN-ï§ as the immunizing antigen. IgG1 antibody was purified from ascites fluid on a Protein A affinity column.
Buffer
PBS
Related Product Information for anti-IFN-alpha antibody
Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,725 Da
NCBI Official Full Name
interferon alpha-1/13
NCBI Official Synonym Full Names
interferon, alpha 13
NCBI Official Symbol
IFNA13
NCBI Protein Information
interferon alpha-1/13; leIF D; IFN-alpha-1/13; interferon alpha-D
UniProt Protein Name
Interferon alpha-1/13
UniProt Gene Name
IFNA1
UniProt Synonym Gene Names
IFN-alpha-1/13; LeIF D
UniProt Entry Name
IFNA1_HUMAN
Uniprot Description
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Ref.15
Subcellular location: Secreted.
Polymorphism: Two forms exist; alpha-1a (shown here) and alpha-1b.
Miscellaneous: Interferons alpha-1 and alpha-13 have identical protein sequences.
Sequence similarities: Belongs to the alpha/beta interferon family.
Research Articles on IFN-alpha
1. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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Product Notes
The IFN-alpha ifna1 (Catalog #AAA690324) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human IFN-alpha reacts with Human and may cross-react with other species as described in the data sheet. ELISA: This antibody can be used at a concentration of 1-2 ug/ml, as a capture antibody in conjunction with a compatible secondary reagent to yield satisfactory results in a sandwich ELISA. Researchers should empirically determine the suitability of the IFN-alpha ifna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFN-alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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