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Western blot (WB) (Western blot analysis of Iba1 on human PBL whole cell lysate using anti-Iba1 antibody at 1/1,000 dilution.)

Mouse Iba1 Monoclonal Antibody | anti-Iba1 antibody

Iba1

Gene Names
AIF1; IBA1; IRT1; AIF-1; IRT-1
Reactivity
Human, Mouse, Rat
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Pro A affinity purified
Synonyms
Iba1; Monoclonal Antibody; AIF 1 antibody;AIF-1 antibody;Aif1 antibody;AIF1 protein antibody;AIF1_HUMAN antibody;Allograft inflammatory factor 1 antibody;Allograft inflammatory factor 1 splice variant G antibody;allograft inflammatory factor-1 splice variant Hara-1 antibody;balloon angioplasty responsive transcription antibody;BART 1 antibody;G1 antibody;G1 putative splice variant of allograft inflamatory factor 1 antibody;IBA 1 antibody;; anti-Iba1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
JB24-42
Purity/Purification
Pro A affinity purified
Form/Format
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Sequence Length
93
Applicable Applications for anti-Iba1 antibody
Western Blot (WB); Immunocytochemistry (ICC); Immunohistochemistry (IHC); Flow Cytometry (FC); Immunoprecipitation (IP).
Immunogen
protein
Subcellular location
Cytoplasm, cytoskeleton.
Positive control
Human PBL whole cell lysate, rat brain, rat C6 glioblastoma tissue.
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.

Western blot (WB)

(Western blot analysis of Iba1 on human PBL whole cell lysate using anti-Iba1 antibody at 1/1,000 dilution.)

Western blot (WB) (Western blot analysis of Iba1 on human PBL whole cell lysate using anti-Iba1 antibody at 1/1,000 dilution.)

Immunohistochemical (IHC)

(Immunohistochemical analysis of paraffinembedded rat C6 glioblastoma tissue using anti-Iba1 antibody. Counter stained with hematoxylin.)

Immunohistochemical (IHC) (Immunohistochemical analysis of paraffinembedded rat C6 glioblastoma tissue using anti-Iba1 antibody. Counter stained with hematoxylin.)
Related Product Information for anti-Iba1 antibody
Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
199
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17kDa
NCBI Official Full Name
allograft inflammatory factor 1 isoform 1
NCBI Official Synonym Full Names
allograft inflammatory factor 1
NCBI Official Symbol
AIF1
NCBI Official Synonym Symbols
IBA1; IRT1; AIF-1; IRT-1
NCBI Protein Information
allograft inflammatory factor 1
UniProt Protein Name
Allograft inflammatory factor 1
UniProt Gene Name
AIF1
UniProt Synonym Gene Names
G1; IBA1; AIF-1

NCBI Description

This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]

Uniprot Description

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Research Articles on Iba1

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Product Notes

The Iba1 aif1 (Catalog #AAA8535056) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Iba1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Iba1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunocytochemistry (ICC); Immunohistochemistry (IHC); Flow Cytometry (FC); Immunoprecipitation (IP). Researchers should empirically determine the suitability of the Iba1 aif1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Iba1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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