Mouse anti-Human HSNF2H Monoclonal Antibody | anti-HSNF2H antibody

HSNF2H (SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin Subfamily A Member 5, SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin A5, Sucrose Nonfermenting Protein 2 Homolog, SMARCA5, SNF2H, WCRF135) (HRP)

Cat. Num. AAA6244123

• Gene Names: SMARCA5; ISWI; SNF2H; hISWI; hSNF2H; WCRF135
• Reactivity: Human
• Applications: Immunocytochemistry, Western Blot
• Purity: Purified by Protein G Affinity Chromatography
• Synonyms: HSNF2H; Monoclonal Antibody; HSNF2H (SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin Subfamily A Member 5; SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin A5; Sucrose Nonfermenting Protein 2 Homolog; SMARCA5; SNF2H; WCRF135) (HRP); anti-HSNF2H antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 13A199
• Specificity: Recognizes human HSNF2H.
• Purity/Purification: Purified by Protein G Affinity Chromatography
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).

• Applicable Applications for anti-HSNF2H antibody: Immunocytochemistry (ICC), Western Blot (WB)
• Immunogen: Recombinant corresponding to human HSNF2H fused to GST-tag.
• Conjugate: HRP
• Preparation and Storage: Store at -20 degree C.

Immunocytochemistry (ICC)

(Immunocytochemistry Analysis: Representative lot data. Confocal fluorescent analysis of HeLa and A431 cells using hSNF2H (Red). Actin filaments have been labeled with Alexa Fluor® 488 dye-Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains the nucleus.)

Western Blot (WB)

(Western Blotting analysis: Representative lot data. HeLa cell lysate was probed with hSNF2H (0.5ug/ml). Proteins were visualized using a Goat Mouse IgG secondary antibody conjugated to HRP and visualized using a chemiluminescence detection system. Arrow indicates hSNF2H (~130kD).)

Product Categories/Family for anti-HSNF2H antibody

Antibodies; Transcription Factors

References

1. Gigek, C.O., et al. (2011). Cancer Invest. 29(2):162-166. 2. Precht, P., et al. (2010). Mol Immunol. 47(11- 12):2038-2046. 3. Vargova, J., et al. (2009): Front Biosci (Elite Ed). 1:553-559. 4. Lazzaro, M.A. and Picketts, D.J. (2001). J Neurochem. 77(4):1145-1156.

NCBI and Uniprot Product Information

• NCBI GI #: 325651836
• NCBI GeneID: 8467
• NCBI Accession #: NP_003592
• NCBI GenBank Nucleotide #: NM_003601
• UniProt Accession #: O60264
• Molecular Weight: 122kDa
• NCBI Official Full Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
• NCBI Official Synonym Full Names: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
• NCBI Official Symbol: SMARCA5
• NCBI Official Synonym Symbols: ISWI; SNF2H; hISWI; hSNF2H; WCRF135
• NCBI Protein Information: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
• UniProt Protein Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
• UniProt Gene Name: SMARCA5
• UniProt Synonym Gene Names: SNF2H; WCRF135; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; hSNF2H
• UniProt Entry Name: SMCA5_HUMAN

NCBI Description

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]