Mouse anti-Human Hox B7 Monoclonal Antibody | anti-HOXB7 antibody

Hox B7 (Homeobox B7)

Cat. Num. AAA603234

• Gene Names: HOXB7; HOX2; HOX2C; HHO.C1; Hox-2.3
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Hox B7; Monoclonal Antibody; Hox B7 (Homeobox B7); Anti -Hox B7 (Homeobox B7); anti-HOXB7 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 8C192
• Specificity: Recognizes human Hox B7.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

• Applicable Applications for anti-HOXB7 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western Blotting: 1:1000-1:2000
• Immunogen: Partial sequence of recombinant full-length protein to human Hox B7
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Western Blot (WB)

(Detection of human HOXB7 by Western blot. Samples: Whole cell lysate (50 μg) from A2058 cells. Predicted molecular weight: 25 kD)

Product Categories/Family for anti-HOXB7 antibody

Antibodies; Abs to Homeobox (HOX)

NCBI and Uniprot Product Information

• NCBI GI #: 85068580
• NCBI GeneID: 3217
• NCBI Accession #: NP_004493.3
• NCBI GenBank Nucleotide #: NM_004502.3
• UniProt Accession #: P09629; Q15957; Q53FN3; Q96BQ6; A8K3N8; Q9HB12; Q9HB28
• Molecular Weight: 24,015 Da
• NCBI Official Full Name: homeobox protein Hox-B7
• NCBI Official Synonym Full Names: homeobox B7
• NCBI Official Symbol: HOXB7
• NCBI Official Synonym Symbols: HOX2; HOX2C; HHO.C1; Hox-2.3
• NCBI Protein Information: homeobox protein Hox-B7; homeo box 2C; homeo box B7; OTTHUMP00000216944; homeo box c1 protein; homeobox protein HHO.C1; homeobox protein Hox-2C
• UniProt Protein Name: Homeobox protein Hox-B7
• Protein Family: Homeobox protein
• UniProt Gene Name: HOXB7
• UniProt Synonym Gene Names: HOX2C
• UniProt Entry Name: HXB7_HUMAN

NCBI Description

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq]

Uniprot Description

HOXB7: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.

Protein type: Motility/polarity/chemotaxis; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: anterior/posterior pattern formation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; myeloid cell differentiation; embryonic skeletal morphogenesis