Dilution Information
Rabbit anti-Human HMGA2 Monoclonal Antibody | anti-HMGA2 antibody
HMGA2 (EP398)
Reactivity
Human
Synonyms
HMGA2; Monoclonal Antibody; HMGA2 (EP398); hmga2; anti-hmga2; high-mobility group at-hook 2; anti-high-mobility group; BABL; HMGI C; HMGIC; LIPO; anti-HMGI-C; anti HMGI-C; anti-HMGI C; anti-HMGIC; anti HMGI C; anti HMGIC; anti-HMGA2; anti HMGA2; High Mobility Group AT-Hook 2; High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C; High Mobility Group Protein HMGI-C; High Mobility Group AT-Hook Protein 2; HMGA2/KRT121P Fusion; HMGI-C; or SRS5; anti-High Mobility Group AT-Hook 2; anti High Mobility Group AT-Hook 2; anti-High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C; anti High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C; anti-High Mobility Group Protein HMGI-C; anti High Mobility Group Protein HMGI-C; anti-BABL; anti BABL; anti-LIPO; anti LIPO; anti-High Mobility Group AT-Hook Protein 2; anti High Mobility Group AT-Hook Protein 2; anti-HMGA2/KRT121P Fusion; anti HMGA2/KRT121P Fusion; anti-STQTL9; anti STQTL9; anti-or SRS5; anti or SRS5; high mobility group AT hook 2; High mobility group AT hook protein 2; high mobility group protein HMGI C; high mobility group nonhistone chromosomal protein isoform I C; hmga; anti-HMGA2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
EP398
Form/Format
Paraffin, Frozen
HMGA2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
HMGA2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
A synthetic peptide corresponding to residues of the human HMGA2 protein.
Control
Cervix, Lung Squamous Cell Carcinoma, Papillary Thyroid Carcinoma
Localization
Nuclear
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(HMGA2 Antibody Immunohistochemistry on an FFPE Lung Squamous Cell Carcinoma Tissue)
Immunohistochemistry (IHC)
(HMGA2 Antibody Immunohistochemistry on an FFPE Lung Squamous Cell Carcinoma Tissue)
Related Product Information for anti-HMGA2 antibody
High-mobility group AT-hook 2 (HMGA2) belongs to the architectural transcription factor HMGA family and is encoded by the HMGA2 gene. HMGA2 plays a role in chromosomal organization and transcriptional regulation. HMGA2 has three basic DNA-binding domains (AT-hooks) that bind to AT rich regions of nuclear DNA and alter the structure of DNA to promote the assembly of protein complexes that regulate transcription. With few exceptions, HMGA2 is expressed in humans only during early development, and is reduced to undetectable levels of transcription in adult tissues.
Elevated expression of HMGA2 antibody is found in a variety of human cancers, correlates with metastasis and poor prognosis for patients. High HMGA2 expression have been reported in Pituitary Adenoma, Thyroid Carcinoma, Triple-Negative Breast Carcinoma, Breast Carcinoma, Lung Adenocarcinoma, Colorectal Carcinoma, Hepatoblastoma, Pancreatic Adenocarcinoma, Conventional and Intramuscular Lipoma, Liposarcoma, Gastric, and Ovarian Tumors and other conditions.. HMGA2 is expressed in most conventional and intramuscular lipomas and can aid in differentiating between Lipomas from dedifferentiated Liposarcomas and distinguishing areas of tumor from normal adipose tissue. In Mesenchymal tumors, HMGA2 antiboy is expressed in benign Fibrous Histiocytoma, Nodular Fasciitis, and Vulvovaginal Angiomyxoma. In Thyroid Carcinomas, upregulation of HMGA2 can distinguish between benign and malignant Follicular neoplasias.
Elevated expression of HMGA2 antibody is found in a variety of human cancers, correlates with metastasis and poor prognosis for patients. High HMGA2 expression have been reported in Pituitary Adenoma, Thyroid Carcinoma, Triple-Negative Breast Carcinoma, Breast Carcinoma, Lung Adenocarcinoma, Colorectal Carcinoma, Hepatoblastoma, Pancreatic Adenocarcinoma, Conventional and Intramuscular Lipoma, Liposarcoma, Gastric, and Ovarian Tumors and other conditions.. HMGA2 is expressed in most conventional and intramuscular lipomas and can aid in differentiating between Lipomas from dedifferentiated Liposarcomas and distinguishing areas of tumor from normal adipose tissue. In Mesenchymal tumors, HMGA2 antiboy is expressed in benign Fibrous Histiocytoma, Nodular Fasciitis, and Vulvovaginal Angiomyxoma. In Thyroid Carcinomas, upregulation of HMGA2 can distinguish between benign and malignant Follicular neoplasias.
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Product Notes
The HMGA2 (Catalog #AAA370495) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMGA2 (EP398) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "HMGA2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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