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Immunohistochemistry (IHC) (Anti-HGF antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.)

Mouse anti-Human HGF/Hepatocyte Growth Factor Monoclonal Antibody | anti-HGF antibody

Anti-HGF/Hepatocyte Growth Factor Antibody (clone 4C12.1)

Gene Names
HGF; SF; HGFB; HPTA; F-TCF; DFNB39
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A purified
Synonyms
HGF/Hepatocyte Growth Factor; Monoclonal Antibody; Anti-HGF/Hepatocyte Growth Factor Antibody (clone 4C12.1); Mouse Monoclonal [clone 7-2] (IgG2a; k) to Human HGF/Hepatocyte Growth Factor; HGF; DFNB39; Hepatocyte growth factor; Hepatopoeitin-A; Hepapoietin A; Hepatopoietin-A; Scatter factor); SF; F-TCF; HGFB; HPTA; Scatter factor; anti-HGF antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
4C12.1
Purity/Purification
Protein A purified
Form/Format
10mM PBS, pH 7.4, with 0.2% BSA and 0.09% Sodium Azide
Sequence Length
728
Applicable Applications for anti-HGF antibody
Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 20 ug/ml
Immunogen
Recombinant human HGF protein.
Conjugation
Unconjugated
Preparation and Storage
Stable for 24 months when stored at 2-8 degree C.

Immunohistochemistry (IHC)

(Anti-HGF antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.)

Immunohistochemistry (IHC) (Anti-HGF antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.)
Related Product Information for anti-HGF antibody
growth factor regulates cell growth, cell motility, and morphogenesis byactivating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted bymesenchymal cells and acts as a multi-functional cytokine on cells ofmainly epithelial origin. Its ability to stimulate mitogenesis, cellmotility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.
Product Categories/Family for anti-HGF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,116 Da
NCBI Official Full Name
hepatocyte growth factor isoform 1 preproprotein
NCBI Official Synonym Full Names
hepatocyte growth factor
NCBI Official Symbol
HGF
NCBI Official Synonym Symbols
SF; HGFB; HPTA; F-TCF; DFNB39
NCBI Protein Information
hepatocyte growth factor
UniProt Protein Name
Hepatocyte growth factor
Protein Family
UniProt Gene Name
HGF
UniProt Synonym Gene Names
HPTA; SF

NCBI Description

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]

Uniprot Description

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

Research Articles on HGF

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Product Notes

The HGF hgf (Catalog #AAA2400586) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-HGF/Hepatocyte Growth Factor Antibody (clone 4C12.1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HGF/Hepatocyte Growth Factor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-P: 20 ug/ml. Researchers should empirically determine the suitability of the HGF hgf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HGF/Hepatocyte Growth Factor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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