Western Blot (WB)
(Western Blot analysis of GYG1 expression in transfected 293T cell line by GYG1 polyclonal antibody. Lane 1: GYG1 transfected lysate (37.5kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human, Rat GYG1 Monoclonal Antibody | anti-GYG1 antibody
GYG1 (Glycogenin 1, Glycogenin-1, GN-1, GN1, GYG) (PE)
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western Blot analysis of GYG1 expression in transfected 293T cell line by GYG1 polyclonal antibody. Lane 1: GYG1 transfected lysate (37.5kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of GYG1 expression in transfected 293T cell line by GYG1 polyclonal antibody. Lane 1: GYG1 transfected lysate (37.5kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the glycogenin family. Glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalyzed by glycogen synthase and branching enzyme, to form glycogen. This gene is expressed in muscle and other tissues. Mutations in this gene result in glycogen storage disease XV. This gene has pseudogenes on chromosomes 1, 8 and 13 respectively. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Uniprot Description
glycogenin: Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Defects in GYG1 are the cause of glycogen storage disease type 15 (GSD15). It is a metabolic disorder resulting in muscle weakness, associated with the glycogen depletion in skeletal muscle, and cardiac arrhythmia, associated with the accumulation of abnormal storage material in the heart. The skeletal muscle shows a marked predominance of slow-twitch, oxidative muscle fibers and mitochondrial proliferation. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.4.1.186; Transferase
Chromosomal Location of Human Ortholog: 3q24-q25.1
Cellular Component: membrane; cytosol
Molecular Function: protein binding; metal ion binding; glycogenin glucosyltransferase activity; glucose binding
Biological Process: glycogen biosynthetic process; glycogen catabolic process; carbohydrate metabolic process; glucose metabolic process; pathogenesis
Research Articles on GYG1
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Product Notes
The GYG1 gyg1 (Catalog #AAA6158120) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GYG1 (Glycogenin 1, Glycogenin-1, GN-1, GN1, GYG) (PE) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GYG1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 3ug/ml Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the GYG1 gyg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GYG1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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